Despite its immense length, the linear sequence of the human genome is an incomplete description of our genetic information. Information on genome function and gene regulation is also encoded in the way that the DNA sequence is folded up with proteins within chromosomes and within the nucleus. Our work tries to understand the three-dimensional folding of the genome, and how this controls how our genome functions in normal development and how this may be perturbed in disease.
For details of my research aims and interest please visit my group page at IGGM.
- EU FP7