Leading science, pioneering therapies

The MRC Centre for Regenerative Medicine (CRM) is a research institute based at the University of Edinburgh. Scientists and clinicians study stem cells, disease and tissue repair to advance human health.

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Human oligodendrocytes from an MS patient

Brain cell changes in people with MS revealed

Fresh insights into the types of cells found in the brains of people with multiple sclerosis could help develop improved therapies.

Stem cell-derived dopamine-producing neurons

Cell therapy hope for Parkinson’s Disease resistant neurones

Tilo Kunath and colleagues have developed Parkinson’s Disease resistant dopamine neurones which could improve cell therapies.

Mouse embryo showing expression of BLIMP1 (green) and OTX2 (red). Credit: Man Zhang

New insights into early development of reproductive cells

CRM scientists have identified a new role for the gene regulator Otx2 at a very early stage in development of primordial germ cells (PGCs), the cells that lead to all germ cells.

Spheres of stem cell-derived liver cells (orange) placed on the scaffold. Credit: H Rashidi 2018.

Stem cell liver implants show promise

New research suggests liver tissue grown from stem cells could one day replace the need for liver transplants.