Remyelination in multiple sclerosis group publications

2019

Matjusaitis M, Wagstaff LJ, Martella A, Baranowski B, Blin C, Gogolok S, Williams AC, Pollard SM. 2019. Reprogramming of Fibroblasts to Oligodendrocyte Progenitor-like Cells Using CRISPR/Cas9-Based Synthetic Transcription Factors.Stem Cell Reports.

Becker CElizabeth, Quinn TJ, Williams AC. 2019. Association Between Endothelial Cell Stabilizing Medication and Small Vessel Disease Stroke: A Case-Control Study

Eigel D, Zoupi L, Sekizar S, Welzel PB, Werner C, Williams AC, Newland B. 2019. Cryogel scaffolds for regionally constrained delivery of lysophosphatidylcholine to central nervous system slice cultures: A model of focal demyelination for multiple sclerosis research.Acta Biomater.

Bardile CFerrari, Garcia-Miralles M, Caron NS, Rayan NArul, Langley SR, Harmston N, Rondelli AMaria, Teo RTang Yi, Waltl S, Anderson LM et al.. 2019. Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease.Proc Natl Acad Sci U S A. 116(19):9622-9627.

2018

Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, M Cader Z, Carare RO et al.. 2018. Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.Clin Sci (Lond). 132(8):851-868.

Bergholt MS, Serio A, McKenzie JS, Boyd A, Soares RF, Tillner J, Chiappini C, Wu V, Dannhorn A, Takats Z et al.. 2018. Correlated Heterospectral Lipidomics for Biomolecular Profiling of Remyelination in Multiple Sclerosis.ACS Cent Sci. 4(1):39-51.

Dillenburg A, Ireland G, Holloway RK, Davies CL, Evans FL, Swire M, Bechler ME, Soong D, Yuen TJ, Su GH et al.. 2018. Activin receptors regulate the oligodendrocyte lineage in health and disease.Acta Neuropathol. 135(6):887-906.

Rajani RM, Quick S, Ruigrok SR, Graham D, Harris SE, Verhaaren BFJ, Fornage M, Seshadri S, Atanur SS, Dominiczak AF et al.. 2018. Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats.Sci Transl Med. 10(448)

2017

Choileain SNi, Hay J, Thomas J, Williams AC, Vermeren MM, Benezech C, Gomez-Salazar M, Hugues OR, Vermeren S, Howie SEM et al.. 2017. TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells.Sci Signal. 10(502)

Rajani RM, Williams AC. 2017. Endothelial cell-oligodendrocyte interactions in small vessel disease and aging.Clin Sci (Lond). 131(5):369-379.

Medina-Rodríguez EMaría, Bribián A, Boyd A, Palomo V, Pastor J, Lagares A, Gil C, Martínez A, Williams AC, de Castro F. 2017. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis.Sci Rep. 7:43545.

Zandee SElizabeth, O'Connor RAnthony, Mair I, Leech MDawn, Williams AC, Anderton SMark. 2017. IL-10-producing, ST2-expressing Foxp3(+) T cells in multiple sclerosis brain lesions.Immunol Cell Biol.

Dombrowski Y, O'Hagan T, Dittmer M, Penalva R, Mayoral SR, Bankhead P, Fleville S, Eleftheriadis G, Zhao C, Naughton M et al.. 2017. Regulatory T cells promote myelin regeneration in the central nervous system.Nat Neurosci.

2016

Ashworth BEve, Stephens E, Bartlett CA, Serghiou S, Giacci MK, Williams AC, Hart NS, Fitzgerald M. 2016. Comparative assessment of phototherapy protocols for reduction of oxidative stress in partially transected spinal cord slices undergoing secondary degeneration.BMC Neurosci. 17(1):21.

Ashworth BEve, Stephens E, Bartlett CA, Serghiou S, Giacci MK, Williams AC, Hart NS, Fitzgerald M. 2016. Comparative assessment of phototherapy protocols for reduction of oxidative stress in partially transected spinal cord slices undergoing secondary degenerationBMC Neuroscience. 17212626147216171520122012536201024123278354024299487230974279401267754940816102902011253227427(1)

2015

Lumley R, Davenport R, Williams AC. 2015. Most Scottish neurologists do not apply the 2010 McDonald criteria when diagnosing multiple sclerosisThe Journal of the Royal College of Physicians of Edinburgh. 45(1):23-26.

Lindner M, mmler Kü, Arthur A, Brunner S, Elliott C, McElroy D, Mohan H, Williams AC, Edgar JM, Schuh C et al.. 2015. Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9Brain. 138(7):1875-1893.

Rittchen S, Boyd A, Burns A, Park J, Fahmy TM, Metcalfe S, Williams AC. 2015. Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF).Biomaterials. 56:78-85.

Jarjour AA, Boyd A, Dow LE, Holloway RK, Goebbels S, Humbert PO, Williams AC, ffrench-Constant C. 2015. The polarity protein scribble regulates myelination and remyelination in the central nervous system.PLoS Biol. 13(3):e1002107.

2014

Münzel E, Becker CG, Becker T, Williams AC. 2014. Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age.Acta Neuropathol Commun. 2(1):77.

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