Ontogeny of haematopoietic stem cells group publications

2019

Easterbrook J, Rybtsov S, Gordon-Keylock S, Ivanovs A, Taoudi S, Anderson RA, Medvinsky AL. 2019. Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo.Stem Cell Reports. 12(5):1056-1068.

2018

Buchtler S, Grill A, Hofmarksrichter S, Stöckert P, Schiechl-Brachner G, Gomez MRodriguez, Neumayer S, Schmidbauer K, Talke Y, Klinkhammer BM et al.. 2018. Cellular Origin and Functional Relevance of Collagen I Production in the Kidney.J Am Soc Nephrol. 29(7):1859-1873.

Senserrich J, Batsivari A, Rybtsov S, Gordon-Keylock S, Souilhol C, Buchholz F, Hills D, Zhao S, Medvinsky AL. 2018. Analysis of Runx1 Using Induced Gene Ablation Reveals Its Essential Role in Pre-liver HSC Development and Limitations of an In Vivo Approach.Stem Cell Reports. 11(3):784-794.

2017

Batsivari A, Rybtsov S, Souilhol C, Binagui-Casas A, Hills D, Zhao S, Travers P, Medvinsky AL. 2017. Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture.Stem Cell Reports. 8(6):1549-1562.

McGarvey AC, Rybtsov S, Souilhol C, Tamagno S, Rice R, Hills D, Godwin D, Rice D, Tomlinson SR, Medvinsky AL. 2017. A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation.J Exp Med. 214(12):3731-3751.

Ivanovs A, Rybtsov S, Ng ES, Stanley EG, Elefanty AG, Medvinsky AL. 2017. Human haematopoietic stem cell development: from the embryo to the dish.Development. 144(13):2323-2337.

Redgrave RE, Tual-Chalot S, Davison BJ, Singh E, Hall D, Amirrasouli MM, Gilchrist D, Medvinsky AL, Arthur HM. 2017. Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.Stem Cell Reports. 8(5):1287-1298.

2016

Mirantes C, Dosil MAlba, Hills D, Yang J, Eritja N, Santacana M, Gatius S, Vilardell F, Medvinsky AL, Matias-Guiu X et al.. 2016. Deletion of Pten in CD45-expressing cells leads to development of T-cell lymphoblastic lymphoma but not myeloid malignancies.Blood. 127(15):1907-11.

Souilhol C, Lendinez JG, Rybtsov S, Murphy F, Wilson H, Hills D, Batsivari A, Binagui-Casas A, McGarvey AC, H MacDonald R et al.. 2016. Developing HSCs become Notch independent by the end of maturation in the AGM region.Blood. 128(12):1567-77.

Ramasamy SK, Kusumbe AP, Schiller M, Zeuschner D, M Bixel G, Milia C, Gamrekelashvili J, Limbourg A, Medvinsky AL, Santoro MM et al.. 2016. Blood flow controls bone vascular function and osteogenesis.Nat Commun. 7:13601.

Ciau-Uitz A, Patient R, Medvinsky AL. 2016. Ontogeny of the Hematopoietic System. In: Ratcliffe, M.J.H. (Editor in Chief), Encyclopedia of Immunobiology, Vol. 1, pp. 1–14. Encyclopedia of Immunobiology. Vol 1

Rybtsov S, Ivanovs A, Zhao S, Medvinsky AL. 2016. Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver.Development. 143(8):1284-9.

Souilhol C, le Gonneau C, Lendinez JG, Batsivari A, Rybtsov S, Wilson H, Morgado-Palacin L, Hills D, Taoudi S, Antonchuk J et al.. 2016. Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells.Nat Commun. 7:10784.

Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, de Wit TDuyvene', Eichinger S, Fibbe W, Green T et al.. 2016. The European Hematology Association Roadmap for European Hematology Research. A Consensus Document.Haematologica.

2015

Economou C, Tsakiridis A, Wymeersch FJ, Gordon-Keylock S, Dewhurst RE, Fisher D, Medvinsky AL, Smith AG, Wilson V. 2015. Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation.BMC Dev Biol. 15(1):35.

Naillat F, Yan W, Karjalainen R, Liakhovitskaia A, Samoylenko A, Xu Q, Sun Z, Shen B, Medvinsky AL, Quaggin S et al.. 2015. Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.Exp Cell Res. 332(2):163-78.

Ivanovs A, Medvinsky AL. 2015. In search of human hematopoietic stem cell identity.Cell Stem Cell. 16(1):5-6.

Medvinsky AL, Livesey FJ. 2015. On human development: lessons from stem cell systems.Development. 142(1):17-20.

2014

Potts KS, Sargeant TJ, Markham JF, Shi W, Biben C, Josefsson EC, Whitehead LW, Rogers KL, Liakhovitskaia A, Smyth GK et al.. 2014. A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo.Blood. 124(17):2725-9.

Rybtsov S, Batsivari A, Bilotkach K, Paruzina D, Senserrich J, Nerushev O, Medvinsky AL. 2014. Tracing the Origin of the HSC Hierarchy Reveals an SCF-Dependent, IL-3-Independent CD43(-) Embryonic Precursor.Stem Cell Reports. 3(3):489-501.

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