Biology of reprogramming group publications

2018

Ward C, Volpe G, Cauchy P, Ptasinska A, Almaghrabi R, Blakemore D, Nafria M, Kestner D, Frampton J, Murphy G et al.. 2018. Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming.Cell Rep. 24(6):1496-1511.e8.

Tosti L, Ashmore J, Tan BSiang Nich, Carbone B, Mistri TK, Wilson V, Tomlinson SR, Kaji K. 2018. Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo.Genome Res. 28(4):592-605.

2017

Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian TV, Kaemena DF, Tosti L, Tan W, Manning JR et al.. 2017. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.Cell Stem Cell.

Aarts M, Georgilis A, Beniazza M, Beolchi P, Banito A, Carroll T, Kulisic M, Kaemena DF, Dharmalingam G, Martin N et al.. 2017. Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.Genes Dev. 31(20):2085-2098.

2015

Kranc KR, Oliveira DV, Armesilla-Diaz A, Pacheco-Leyva I, Matias ACatarina, Escapa ALuisa, Subramani C, Wheadon H, Trindade M, Nichols J et al.. 2015. Acute Loss of Cited2 Impairs Nanog Expression and Decreases Self-Renewal of Mouse Embryonic Stem CellsSTEM CELLS. 33(3):699-712.

Chantzoura E, Skylaki S, Menendez S, Kim S-I, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K. 2015. Reprogramming Roadblocks Are System Dependent.Stem Cell Reports. 5(3):350-64.

2014

Ruetz T, Kaji K. 2014. Routes to induced pluripotent stem cells.Curr Opin Genet Dev. 28C:38-42.

Santos RLDos, Tosti L, Radzisheuskaya A, Caballero IM, Kaji K, Hendrich B, Silva J. 2014. MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner.Cell Stem Cell. 15(1):102-10.

2013

Hamilton WB, Kaji K, Kunath T. 2013. ERK2 suppresses self-renewal capacity of embryonic stem cells, but is not required for multi-lineage commitment.PLoS One. 8(4):e60907.

O'Malley J, Skylaki S, Iwabuchi KA, Chantzoura E, Ruetz T, Johnsson A, Tomlinson SR, Linnarsson S, Kaji K. 2013. High-resolution analysis with novel cell-surface markers identifies routes to iPS cells.Nature. 499(7456):88-91.

2012

Hammachi F, Morrison GM, Sharov AA, Livigni A, Narayan S, Papapetrou EP, O'Malley J, Kaji K, Ko MSH, Ptashne M et al.. 2012. Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency.Cell Rep. 1(2):99-109.

2009

Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K. 2009. Virus-free induction of pluripotency and subsequent excision of reprogramming factors.Nature. 458(7239):771-5.

Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, Cowling R, Wang W, Liu P, Gertsenstein M et al.. 2009. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells.Nature. 458(7239):766-70.

O'Malley J, Woltjen K, Kaji K. 2009. New strategies to generate induced pluripotent stem cells.Curr Opin Biotechnol. 20(5):516-21.

2007

Kaji K, Nichols J, Hendrich B. 2007. Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.Development. 134(6):1123-32.

2006

Kaji K, Caballero IMartín, MacLeod R, Nichols J, Wilson V, Hendrich B. 2006. The NuRD component Mbd3 is required for pluripotency of embryonic stem cells.Nat Cell Biol. 8(3):285-92.

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