Leading science, pioneering therapies

Integrated chemical biophysics

Professor Auer’s research is focused on the development and application of miniaturised, ultra high-throughput screening platforms for the identification and validation of lead compounds for drug discovery and tool compounds for basic research.

Aims and areas of interest

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His “Integrated Chemical Biophysics” platforms (ICB) include in-silico design and screening, tagged one-bead one compound library production and screening on the surface of beads and chips, in solution, in cells and in model organisms. ICB platforms combine chemical, biological, and physical approaches to overcome many of the limitations of the current industrial early drug-discovery process. Using the flexible post-synthesis - post screening tagging technologies developed in the Auer group, both label free and single molecule fluorescence detection technologies are combined into seamless processes.