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Transgenic animal models of cardiovascular disease.

TitleTransgenic animal models of cardiovascular disease.
Publication TypeJournal Article
Year of Publication1992
AuthorsBarrett G, Mullins JJ
JournalCurr Opin Biotechnol
Date Published1992 Dec
KeywordsAnimals, Animals, Genetically Modified, Apolipoprotein A-I, Arteriosclerosis, Blood Pressure, Cardiomegaly, Cardiovascular Diseases, Cholesterol, HDL, Disease Models, Animal, Humans, Hypertension, Mice, Mice, Transgenic, Renin, Renin-Angiotensin System

Transgenic experimentation has become a crucial part of hypertension and atherosclerosis research, and is growing more important in several other areas of cardiovascular disease. It has recently made a particular contribution to understanding the role of the renin-angiotensin system in controlling hypertension. The study of blood pressure regulation, cardiac hypertrophy, atherogenesis and thrombosis are also benefiting from the transgenic approach.

Alternate JournalCurr. Opin. Biotechnol.
PubMed ID1369120