| Title | Transgenic animal models of cardiovascular disease. |
| Publication Type | Journal Article |
| Year of Publication | 1992 |
| Authors | Barrett G, Mullins JJ |
| Journal | Curr Opin Biotechnol |
| Volume | 3 |
| Issue | 6 |
| Pagination | 637-40 |
| Date Published | 1992 Dec |
| ISSN | 0958-1669 |
| Keywords | Animals, Animals, Genetically Modified, Apolipoprotein A-I, Arteriosclerosis, Blood Pressure, Cardiomegaly, Cardiovascular Diseases, Cholesterol, HDL, Disease Models, Animal, Humans, Hypertension, Mice, Mice, Transgenic, Renin, Renin-Angiotensin System |
| Abstract | Transgenic experimentation has become a crucial part of hypertension and atherosclerosis research, and is growing more important in several other areas of cardiovascular disease. It has recently made a particular contribution to understanding the role of the renin-angiotensin system in controlling hypertension. The study of blood pressure regulation, cardiac hypertrophy, atherogenesis and thrombosis are also benefiting from the transgenic approach. |
| Alternate Journal | Curr. Opin. Biotechnol. |
| PubMed ID | 1369120 |
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