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Transgenic animal models of cardiovascular disease.

TitleTransgenic animal models of cardiovascular disease.
Publication TypeJournal Article
Year of Publication1992
AuthorsBarrett G, Mullins JJ
JournalCurr Opin Biotechnol
Volume3
Issue6
Pagination637-40
Date Published1992 Dec
ISSN0958-1669
KeywordsAnimals, Animals, Genetically Modified, Apolipoprotein A-I, Arteriosclerosis, Blood Pressure, Cardiomegaly, Cardiovascular Diseases, Cholesterol, HDL, Disease Models, Animal, Humans, Hypertension, Mice, Mice, Transgenic, Renin, Renin-Angiotensin System
Abstract

Transgenic experimentation has become a crucial part of hypertension and atherosclerosis research, and is growing more important in several other areas of cardiovascular disease. It has recently made a particular contribution to understanding the role of the renin-angiotensin system in controlling hypertension. The study of blood pressure regulation, cardiac hypertrophy, atherogenesis and thrombosis are also benefiting from the transgenic approach.

Alternate JournalCurr. Opin. Biotechnol.
PubMed ID1369120