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Regenerative medicine. Knocking on the door to successful hepatocyte transplantation.

TitleRegenerative medicine. Knocking on the door to successful hepatocyte transplantation.
Publication TypeJournal Article
Year of Publication2014
AuthorsForbes SJ, Alison MR
JournalNat Rev Gastroenterol Hepatol
Volume11
Issue5
Pagination277-8
Date Published2014 May
ISSN1759-5053
Abstract

With the ongoing shortage of livers available for transplantation, attention has turned to cell-based approaches to support liver function and enable liver regeneration. However, hepatocyte transplantation is beset with problems and a clinically adoptable strategy is lacking. How can a plentiful supply of hepatocyte-like cells with long-term proliferation be generated?

DOI10.1038/nrgastro.2014.44
Alternate JournalNat Rev Gastroenterol Hepatol
PubMed ID24662276
Publication institute
CRM