Title | Physical forces in myelination and repair: a question of balance? |
Publication Type | Journal Article |
Year of Publication | 2009 |
Authors | Bauer NG, ffrench-Constant C |
Journal | J Biol |
Volume | 8 |
Issue | 8 |
Pagination | 78 |
Date Published | 2009 |
ISSN | 1475-4924 |
Keywords | Animals, Cell Adhesion, Cell Shape, Extracellular Matrix, Humans, Mechanotransduction, Cellular, Multiple Sclerosis, Myelin Sheath, Regeneration |
Abstract | A recent report in BMC Cell Biology examines how the balance of extracellular forces and intracellular contractions regulate the shape changes required for oligodendrocyte myelination. A failure of remyelination such as seen in multiple sclerosis could be caused by loss of this balance. |
DOI | 10.1186/jbiol169 |
Alternate Journal | J. Biol. |
PubMed ID | 19804608 |
PubMed Central ID | PMC2776912 |