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Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.

TitleMild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.
Publication TypeJournal Article
Year of Publication2011
AuthorsBell KF, Al-Mubarak B, Fowler JH, Baxter PS, Gupta K, Tsujita T, Chowdhry S, Patani R, Chandran S, Horsburgh K, Hayes JD, Hardingham GE
JournalProc Natl Acad Sci U S A
Volume108
Issue1
PaginationE1-2; author reply E3-4
Date Published2011 Jan 4
ISSN1091-6490
KeywordsAnimals, Astrocytes, Cells, Cultured, Gene Expression Regulation, Enzymologic, Heme Oxygenase (Decyclizing), Hydrogen Peroxide, Ischemic Preconditioning, Neurons, Neuroprotective Agents, NF-E2-Related Factor 2, Oxidative Stress, Oxidoreductases Acting on Sulfur Group Donors, Rats
DOI10.1073/pnas.1015229108
Alternate JournalProc. Natl. Acad. Sci. U.S.A.
PubMed ID21177433
PubMed Central IDPMC3017195
Grant ListG0902044 / / Medical Research Council / United Kingdom
G0902044(94018) / / Medical Research Council / United Kingdom
/ / Canadian Institutes of Health Research / Canada
/ / Medical Research Council / United Kingdom
/ / Wellcome Trust / United Kingdom