|Title||Gene targeting and synaptic plasticity.|
|Publication Type||Journal Article|
|Year of Publication||1994|
|Journal||Curr Opin Neurobiol|
|Date Published||1994 Oct|
|Keywords||Animals, Behavior, Animal, Gene Targeting, Humans, Learning, Mice, Mice, Knockout, Models, Neurological, Mutation, Nerve Tissue Proteins, Neuronal Plasticity, Neurons, Protein Kinases, Receptors, N-Methyl-D-Aspartate, Second Messenger Systems, Synapses, Synaptic Vesicles|
Gene targeting is revealing new molecular functions by creating very specific developmental, physiological and behavioral perturbations, and providing new insights into biochemical pathways underlying synaptic plasticity. Recent studies of mice carrying mutations in genes thought to be involved in modulating synaptic transmission have been subject to integrated biochemical, physiological and behavioral analyses.
|Alternate Journal||Curr. Opin. Neurobiol.|