Sally Lowell

Position:

Wellcome Trust Senior Research Fellow

Telephone:

0131 651 9500

Display email:

sally.lowell@ed.ac.uk

Biography:

• PhD with Fiona Watt at CRUK
• Postdoc with David Anderson at Caltech
• Postdoc with Austin Smith at the University of Edinburgh
• Wellcome Trust Career Development Fellow at the University of Edinburgh

• Wellcome Trust Senior Fellow at the University of Edinburgh

Publications

2019

Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation Malaguti, Mattias, Migueles Rosa Portero, Blin Guillaume, Lin Chia-Yi, and Lowell Sally , (2019)

Biotic analogies for self-organising cities Narraway, C, Davis O, Lowell Sally, Lythgoe K A., Turner S J., and Marshall S , (2019)

N-cadherin stabilises neural identity by dampening anti-neural signals Punovuori, Karolina, Migueles Rosa Portero, Malaguti Mattias, Blin Guillaume, Macleod K, Carragher Neil O., Pieters T, van Roy F, Stemmler MP, and Lowell Sally , 16/07/2019, (2019)

Nessys: A new set of tools for the automated detection of nuclei within intact tissues and dense 3D cultures. Blin, Guillaume, Sadurska Daina, Migueles Rosa Portero, Chen Naiming, Watson Julia A., and Lowell Sally , PLoS Biol, 2019 Aug, Volume 17, Issue 8, p.e3000388, (2019)

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging. Wisniewski, Darren, Lowell Sally, and Blin Guillaume , J Vis Exp, 2019 Apr 30, Issue 146, (2019)

2018

Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells. Blin, Guillaume, Wisniewski Darren, Picart Catherine, Théry Manuel, Puceat Michel, and Lowell Sally , Development, 2018 Sep 21, Volume 145, Issue 18, (2018)

BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity. Row, Richard H., Pegg Amy, Kinney Brian A., Farr Gist H., Maves Lisa, Lowell Sally, Wilson Valerie, and Martin Benjamin L. , Elife, 2018 Jun 07, Volume 7, (2018)

2017

Atoh1 in sensory hair cell development: constraints and cofactors. Costa, Aida, Powell Lynn M., Lowell Sally, and Jarman Andrew P. , Semin Cell Dev Biol, 2017 05, Volume 65, p.60-68, (2017)

Polarity Reversal by Centrosome Repositioning Primes Cell Scattering during Epithelial-to-Mesenchymal Transition. Burute, Mithila, Prioux Magali, Blin Guillaume, Truchet Sandrine, Letort Gaëlle, Tseng Qingzong, Bessy Thomas, Lowell Sally, Young Joanne, Filhol Odile, et al. , Dev Cell, 2017 Jan 23, Volume 40, Issue 2, p.168-184, (2017)

2016

Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons. Qiu, Jing, McQueen Jamie, Bilican Bilada, Dando Owen, Magnani Dario, Punovuori Karolina, Selvaraj Bhuvaneish T., Livesey Matthew, Haghi Ghazal, Heron Samuel, et al. , Elife, 2016 Oct 01, Volume 5, (2016)

2015

Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression. Laing, Adam F., Lowell Sally, and Brickman Joshua M. , Dev Biol, 2015 Jan 1, Volume 397, Issue 1, p.56-66, (2015)

2014

Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors. Tsakiridis, Anestis, Huang Yali, Blin Guillaume, Skylaki Stavroula, Wymeersch Filip J., Osorno Rodrigo, Economou Constantinos, Karagianni Eleni, Zhao Suling, Lowell Sally, et al. , Development, 2014 Mar, Volume 141, Issue 6, p.1209-21, (2014)

2013

Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin. Malaguti, Mattias, Nistor Paul A., Blin Guillaume, Pegg Amy, Zhou Xinzhi, and Lowell Sally , Elife, 2013, Volume 2, p.e01197, (2013)

Haematopoietic differentiation is inhibited when Notch activity is enhanced in FLK1(+) mesoderm progenitors. Huang, Caoxin, Jackson Melany, Samuel Kay, A Taylor Helen, Lowell Sally, and Forrester Lesley M. , Stem Cell Res, 2013 Nov, Volume 11, Issue 3, p.1273-87, (2013)

Getting the measure of things: the physical biology of stem cells. Lowell, Sally , Development, 2013 Oct, Volume 140, Issue 20, p.4125-8, (2013)

Tcf15 primes pluripotent cells for differentiation. Davies, Owen R., Lin Chia-Yi, Radzisheuskaya Aliaksandra, Zhou Xinzhi, Taube Jessica, Blin Guillaume, Waterhouse Anna, Smith A G., and Lowell Sally , Cell Rep, 2013 Feb 21, Volume 3, Issue 2, p.472-84, (2013)

Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity. Zhou, Xinzhi, Smith A G., Waterhouse Anna, Blin Guillaume, Malaguti Mattias, Lin Chia-Yi, Osorno Rodrigo, Chambers Ian, and Lowell Sally , Stem Cells, 2013 Aug, Volume 31, Issue 8, p.1511-22, (2013)

2012

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Boulter, Luke, Govaere Olivier, Bird Tom G., Radulescu Sorina, Ramachandran Prakash, Pellicoro Antonella, Ridgway Rachel A., Seo Sang Soo, Spee Bart, van Rooijen Nico, et al. , Nat Med, 2012 Apr, Volume 18, Issue 4, p.572-9, (2012)

2006

Notch promotes neural lineage entry by pluripotent embryonic stem cells. Lowell, Sally, Benchoua Alexandra, Heavey Barry, and Smith Austin G. , PLoS Biol, 2006 May, Volume 4, Issue 5, p.e121, (2006)

Stem cells in the genomic age. Lowell, Sally , Genome Biol, 2006, Volume 7, Issue 5, p.315, (2006)

Neural stem cells, neurons, and glia. Pollard, Steven M., Benchoua Alexandra, and Lowell Sally , Methods Enzymol, 2006, Volume 418, p.151-69, (2006)

2003

Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Gabay, Limor, Lowell Sally, Rubin Lee L., and Anderson David J. , Neuron, 2003 Oct 30, Volume 40, Issue 3, p.485-99, (2003)

2002

Epidermal stem cells. Janes, Sam M., Lowell Sally, and Hutter Caroline , J Pathol, 2002 Jul, Volume 197, Issue 4, p.479-91, (2002)

2001

Delta regulates keratinocyte spreading and motility independently of differentiation. Lowell, Sally, and Watt F M. , Mech Dev, 2001 Sep, Volume 107, Issue 1-2, p.133-40, (2001)

2000

Stem cells: You make me feel so glial. Lowell, Sally , Curr Biol, 2000 Aug 24, Volume 10, Issue 16, p.R595-7, (2000)

Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Lowell, Sally, Jones P, Le Roux I, Dunne J, and Watt F M. , Curr Biol, 2000 May 4, Volume 10, Issue 9, p.491-500, (2000)

1999

The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis. Jensen, U B., Lowell Sally, and Watt F M. , Development, 1999 Jun, Volume 126, Issue 11, p.2409-18, (1999)

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