CRM Publications

Nichols J, Davidson D, Taga T, Yoshida K, Chambers I, Smith A.  1996.  Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis.Mech Dev. 57(2):123-31.

Clark AF, Sharp MG, Mullins JJ.  1996.  Gene targeting and its application to basic hypertension research.Clin Sci (Lond). 90(6):435-46.

Lee K, Nichols J, Smith A.  1996.  Identification of a developmentally regulated protein tyrosine phosphatase in embryonic stem cells that is a marker of pluripotential epiblast and early mesoderm.Mech Dev. 59(2):153-64.

Forrester LM, Nagy A, Sam M, Watt A, Stevenson L, Bernstein A, Joyner AL, Wurst W.  1996.  An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro.Proc Natl Acad Sci U S A. 93(4):1677-82.

Tate P, Skarnes W, Bird A.  1996.  The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse.Nat Genet. 12(2):205-8.

Mullins LJ, Mullins JJ.  1996.  Transgenesis in the rat and larger mammals.J Clin Invest. 97(7):1557-60.

Skarnes WC, Moss JE, Hurtley SM, Beddington RS.  1995.  Capturing genes encoding membrane and secreted proteins important for mouse development.Proc Natl Acad Sci U S A. 92(14):6592-6.

Smith AG, De Sousa MA, Kwabi-Addo B, Heppell-Parton A, Impey H, Rabbitts P.  1995.  A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.Nat Genet. 9(4):376-85.

Zmuidzinas A, Fischer KD, Lira SA, Forrester LM, Bryant S, Bernstein A, Barbacid M.  1995.  The vav proto-oncogene is required early in embryogenesis but not for hematopoietic development in vitro.EMBO J. 14(1):1-11.

Nichols J, Chambers I, Smith A.  1994.  Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor.Exp Cell Res. 215(1):237-9.

Mountford P, Zevnik B, Düwel A, Nichols J, Li M, Dani C, Robertson M, Chambers I, Smith A.  1994.  Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.Proc Natl Acad Sci U S A. 91(10):4303-7.

Yoshida K, Chambers I, Nichols J, Smith A, Saito M, Yasukawa K, Shoyab M, Taga T, Kishimoto T.  1994.  Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways.Mech Dev. 45(2):163-71.

Stapleton G, Somma MP, Lavia P.  1993.  Cell type-specific interactions of transcription factors with a housekeeping promoter in vivo.Nucleic Acids Res. 21(10):2465-71.

Whyatt LM, Düwel A, Smith AG, Rathjen PD.  1993.  The responsiveness of embryonic stem cells to alpha and beta interferons provides the basis of an inducible expression system for analysis of developmental control genes.Mol Cell Biol. 13(12):7971-6.

Beddington RS, Rashbass P, Wilson V.  1992.  Brachyury--a gene affecting mouse gastrulation and early organogenesis.Dev Suppl. :157-65.

Smith AG.  1992.  Mouse embryo stem cells: their identification, propagation and manipulation.Semin Cell Biol. 3(6):385-99.

Ure JM, Fiering S, Smith AG.  1992.  A rapid and efficient method for freezing and recovering clones of embryonic stem cells.Trends Genet. 8(1):6.

Sheardown SA, Hooper ML.  1992.  A relationship between gap junction-mediated intercellular communication and the in vitro developmental capacity of murine embryonic stem cells.Exp Cell Res. 198(2):276-82.

Clarke AR, Maandag ER, van Roon M, van der Lugt NM, van der Valk M, Hooper ML, Berns A, H Riele te.  1992.  Requirement for a functional Rb-1 gene in murine development.Nature. 359(6393):328-30.

Dorin JR, Dickinson P, Emslie E, Clarke AR, Dobbie L, Hooper ML, Halford S, Wainwright BJ, Porteous DJ.  1992.  Successful targeting of the mouse cystic fibrosis transmembrane conductance regulator gene in embryonal stem cells.Transgenic Res. 1(2):101-5.

Rashbass P, Cooke LA, Herrmann BG, Beddington RS.  1991.  A cell autonomous function of Brachyury in T/T embryonic stem cell chimaeras.Nature. 353(6342):348-51.

Mombaerts P, Clarke AR, Hooper ML, Tonegawa S.  1991.  Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting.Proc Natl Acad Sci U S A. 88(8):3084-7.

Nichols J, Evans EP, Smith AG.  1990.  Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity.Development. 110(4):1341-8.