CRM Publications

Wilmut I, Sullivan G, Chambers I.  2011.  The evolving biology of cell reprogramming.Philos Trans R Soc Lond B Biol Sci. 366(1575):2183-97.

Tan CLik, Kwok JCF, Patani R, ffrench-Constant C, Chandran S, Fawcett JW.  2011.  Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling.J Neurosci. 31(17):6289-95.

Vernimmen D, Lynch MD, De Gobbi M, Garrick D, Sharpe JA, Sloane-Stanley JA, Smith AG, Higgs DR.  2011.  Polycomb eviction as a new distant enhancer function.Genes Dev. 25(15):1583-8.

Ermakova O, Piszczek L, Luciani L, Cavalli FMG, Ferreira T, Farley D, Rizzo S, Paolicelli RChiara, Al-Banchaabouchi M, Nerlov C et al..  2011.  Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.EMBO Mol Med. 3(1):50-66.

Osorno R, Chambers I.  2011.  Transcription factor heterogeneity and epiblast pluripotency.Philos Trans R Soc Lond B Biol Sci. 366(1575):2230-7.

Navarro P, Moffat M, Mullin NP, Chambers I.  2011.  The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.Hum Genet. 130(2):255-64.

Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MGrazia, Chandran S.  2010.  Cell-mediated neuroprotection in a mouse model of human tauopathy.J Neurosci. 30(30):9973-83.

Afshari FT, Kwok JC, Andrews MR, Blits B, Martin KR, Faissner A, ffrench-Constant C, Fawcett JW.  2010.  Integrin activation or alpha 9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration.Brain. 133(Pt 2):448-64.

Bonfanti P, Claudinot S, Amici AW, Farley A, C Blackburn C, Barrandon Y.  2010.  Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells.Nature. 466(7309):978-82.

Emmerson E, Campbell L, Ashcroft GS, Hardman MJ.  2010.  The phytoestrogen genistein promotes wound healing by multiple independent mechanisms.Mol Cell Endocrinol. 321(2):184-93.

Brown JM, Green J, Neves RPires das, Wallace HAC, Smith AG, Hughes J, Gray N, Taylor S, Wood WG, Higgs DR et al..  2008.  Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.J Cell Biol. 182(6):1083-97.

Depreter MGL, Blair NF, Gaskell TL, Nowell CS, Davern K, Pagliocca A, Stenhouse FH, Farley A, Fraser A, Vrana J et al..  2008.  Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells.Proc Natl Acad Sci U S A. 105(3):961-6.

Hayashi K, Lopes SMChuva de, Kaneda M, Tang F, Hajkova P, Lao K, O'Carroll D, Das PP, Tarakhovsky A, Miska EA et al..  2008.  MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.PLoS One. 3(3):e1738.

Zhao C, Fancy SPJ, ffrench-Constant C, Franklin RJM.  2008.  Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination.Neurobiol Dis. 31(2):209-17.

Mullin NP, Yates A, Rowe AJ, Nijmeijer B, Colby D, Barlow PN, Walkinshaw MD, Chambers I.  2008.  The pluripotency rheostat Nanog functions as a dimer.Biochem J. 411(2):227-31.

Bru T, Clarke C, McGrew MJ, Sang HM, Wilmut I, J Blow J.  2008.  Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts.Exp Cell Res. 314(14):2634-42.

Mackinnon AC, Farnworth SL, Hodkinson PS, Henderson NC, Atkinson KM, Leffler H, Nilsson UJ, Haslett C, Forbes SJ, Sethi T.  2008.  Regulation of alternative macrophage activation by galectin-3.J Immunol. 180(4):2650-8.

Johnson CE, Crawford BE, Stavridis M, Dam GTen, Wat AL, Rushton G, Ward CM, Wilson V, van Kuppevelt TH, Esko JD et al..  2007.  Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells.Stem Cells. 25(8):1913-23.

Pimanda JE, Ottersbach K, Knezevic K, Kinston S, Chan WYI, Wilson NK, Landry J-R, Wood AD, Kolb-Kokocinski A, Green AR et al..  2007.  Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.Proc Natl Acad Sci U S A. 104(45):17692-7.

Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, Robertson M, Vrana J, Jones K, Grotewold L, Smith A.  2007.  Nanog safeguards pluripotency and mediates germline development.Nature. 450(7173):1230-4.

Lowell S, Benchoua A, Heavey B, Smith AG.  2006.  Notch promotes neural lineage entry by pluripotent embryonic stem cells.PLoS Biol. 4(5):e121.

Gomez-Escobar N, Bennett CL, Prieto-Lafuente L, Aebischer T, C Blackburn C, Maizels RM.  2005.  Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function.BMC Biol. 3:8.

Bouhon IA, Kato H, Chandran S, Allen ND.  2005.  Neural differentiation of mouse embryonic stem cells in chemically defined medium.Brain Res Bull. 68(1-2):62-75.

Sherwin JRA, Freeman TC, Stephens RJ, Kimber SJ, Smith AG, Chambers I, Smith SK, Sharkey AM.  2004.  Identification of genes regulated by leukemia-inhibitory factor in the mouse uterus at the time of implantation.Mol Endocrinol. 18(9):2185-95.

Chambers I.  2004.  The molecular basis of pluripotency in mouse embryonic stem cells.Cloning Stem Cells. 6(4):386-91.