CRM Publications

Gómez-López S, Wiskow O, Favaro R, Nicolis SK, Pollard SM, Smith A.  2011.  Sox2 and Pax6 maintain the proliferative and developmental potential of gliogenic neural stem cells In vitro.Glia. 59(11):1588-99.

Navarro P, Moffat M, Mullin NP, Chambers I.  2011.  The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.Hum Genet. 130(2):255-64.

Bialecka M, Wilson V, Deschamps J.  2010.  Cdx mutant axial progenitor cells are rescued by grafting to a wild type environment.Dev Biol. 347(1):228-34.

Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MGrazia, Chandran S.  2010.  Cell-mediated neuroprotection in a mouse model of human tauopathy.J Neurosci. 30(30):9973-83.

Kuijk EW, de Gier J, Lopes SMChuva de, Chambers I, van Pelt AMM, Colenbrander B, Roelen BAJ.  2010.  A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.PLoS One. 5(6):e10987.

Soufi A, Sawasdichai A, Shukla A, Noy P, Dafforn T, Smith C, Jayaraman P-S, Gaston K.  2010.  DNA compaction by the higher-order assembly of PRH/Hex homeodomain protein oligomers.Nucleic Acids Res. 38(21):7513-25.

Canham MA, Sharov AA, Ko MSH, Brickman JM.  2010.  Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript.PLoS Biol. 8(5):e1000379.

Wilson NK, Timms RT, Kinston SJ, Cheng Y-H, S Oram H, Landry J-R, Mullender J, Ottersbach K, Göttgens B.  2010.  Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.Mol Cell Biol. 30(15):3853-63.

Gordon-Keylock S, Jackson M, Huang C, Samuel K, Axton RA, Oostendorp RAJ, A Taylor H, Wilson J, Forrester LM.  2010.  Induction of hematopoietic differentiation of mouse embryonic stem cells by an AGM-derived stromal cell line is not further enhanced by overexpression of HOXB4.Stem Cells Dev. 19(11):1687-98.

Navarro P, Oldfield A, Legoupi J, Festuccia N, Dubois A, Attia M, Schoorlemmer J, Rougeulle C, Chambers I, Avner P.  2010.  Molecular coupling of Tsix regulation and pluripotency.Nature. 468(7322):457-60.

Soufi A, Noy P, Buckle M, Sawasdichai A, Gaston K, Jayaraman P-S.  2009.  CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding.Nucleic Acids Res. 37(10):3288-300.

Ho H-Y, Chang K-H, Nichols J, Li M.  2009.  Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells.Mech Dev. 126(1-2):18-29.

Silva J, Nichols J, Theunissen TW, Guo G, van Oosten AL, Barrandon O, Wray J, Yamanaka S, Chambers I, Smith A.  2009.  Nanog is the gateway to the pluripotent ground state.Cell. 138(4):722-37.

Jacobs FMJ, van Erp S, van der Linden AJA, von Oerthel L, J Burbach PH, Smidt MP.  2009.  Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression.Development. 136(4):531-40.

Chambers I, Tomlinson SR.  2009.  The transcriptional foundation of pluripotency.Development. 136(14):2311-22.

Morrison GM, Oikonomopoulou I, Migueles RPortero, Soneji S, Livigni A, Enver T, Brickman JM.  2008.  Anterior definitive endoderm from ESCs reveals a role for FGF signaling.Cell Stem Cell. 3(4):402-15.

van den Berg DLC, Zhang W, Yates A, Engelen E, Takacs K, Bezstarosti K, Demmers J, Chambers I, Poot RA.  2008.  Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression.Mol Cell Biol. 28(19):5986-95.

Buscarlet M, Perin A, Laing A, Brickman JM, Stifani S.  2008.  Inhibition of cortical neuron differentiation by Groucho/TLE1 requires interaction with WRPW, but not Eh1, repressor peptides.J Biol Chem. 283(36):24881-8.

McGrew MJ, Sherman A, Lillico SG, Ellard FM, Radcliffe PA, Gilhooley HJ, Mitrophanous KA, Cambray N, Wilson V, Sang HM.  2008.  Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity.Development. 135(13):2289-99.

Navarro P, Chambers I, Karwacki-Neisius V, Chureau C, Morey C, Rougeulle C, Avner P.  2008.  Molecular coupling of Xist regulation and pluripotency.Science. 321(5896):1693-5.

Mullin NP, Yates A, Rowe AJ, Nijmeijer B, Colby D, Barlow PN, Walkinshaw MD, Chambers I.  2008.  The pluripotency rheostat Nanog functions as a dimer.Biochem J. 411(2):227-31.

Soufi A, Jayaraman P-S.  2008.  PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate.Biochem J. 412(3):399-413.

Bru T, Clarke C, McGrew MJ, Sang HM, Wilmut I, J Blow J.  2008.  Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts.Exp Cell Res. 314(14):2634-42.

Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, Robertson M, Vrana J, Jones K, Grotewold L, Smith A.  2007.  Nanog safeguards pluripotency and mediates germline development.Nature. 450(7173):1230-4.

Zamparini AL, Watts T, Gardner CE, Tomlinson SR, Johnston GI, Brickman JM.  2006.  Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and NodalDevelopment. 133(18):3709-22.