CRM Publications

Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M et al..  2017.  DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.Proc Natl Acad Sci U S A. 114(36):E7526-E7535.

Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth R, Webb S, Kerr ARW, Lyall MJ et al..  2016.  Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.Cancer Res. 76(10):3097-108.

Illingworth R, Gruenewald-Schneider U, De Sousa D, Webb S, Merusi C, Kerr ARW, James KD, Smith C, Walker R, Andrews R et al..  2015.  Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome.Nucleic Acids Res. 43(2):732-44.

Clouaire T, Webb S, Skene P, Illingworth R, Kerr A, Andrews R, Lee J-H, Skalnik D, Bird A.  2012.  Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.Genes Dev. 26(15):1714-28.

Lynch MD, Smith AG, De Gobbi M, Flenley M, Hughes J, Vernimmen D, Ayyub H, Sharpe JA, Sloane-Stanley JA, Sutherland L et al..  2012.  An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.EMBO J. 31(2):317-29.

Illingworth R, Botting CH, Grimes GR, Bickmore WA, Eskeland R.  2012.  PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.PLoS One. 7(4):e34848.

Deaton AM, Webb S, Kerr ARW, Illingworth R, Guy J, Andrews R, Bird A.  2011.  Cell type-specific DNA methylation at intragenic CpG islands in the immune system.Genome Res. 21(7):1074-86.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G et al..  2011.  Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.Cell Res. 21(9):1332-42.

Vernimmen D, Lynch MD, De Gobbi M, Garrick D, Sharpe JA, Sloane-Stanley JA, Smith AG, Higgs DR.  2011.  Polycomb eviction as a new distant enhancer function.Genes Dev. 25(15):1583-8.

Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr ARW, Deaton A, Andrews R, James KD et al..  2010.  CpG islands influence chromatin structure via the CpG-binding protein Cfp1.Nature. 464(7291):1082-6.

Terrenoire E, McRonald F, Halsall JA, Page P, Illingworth R, A Taylor MR, Davison V, O'Neill LP, Turner BM.  2010.  Immunostaining of modified histones defines high-level features of the human metaphase epigenome.Genome Biol. 11(11):R110.

Skene PJ, Illingworth R, Webb S, Kerr ARW, James KD, Turner DJ, Andrews R, Bird AP.  2010.  Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.Mol Cell. 37(4):457-68.

Illingworth R, Gruenewald-Schneider U, Webb S, Kerr ARW, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP.  2010.  Orphan CpG islands identify numerous conserved promoters in the mammalian genome.PLoS Genet. 6(9):e1001134.

Navarro P, Chambers I.  2010.  Is the umbilical cord a lifeline for regenerative therapy?Cell Cycle. 9(8):1464.

Illingworth R, Bird AP.  2009.  CpG islands--'a rough guide'.FEBS Lett. 583(11):1713-20.

Illingworth R, Kerr A, Desousa D, Jørgensen H, Ellis P, Stalker J, Jackson D, Clee C, Plumb R, Rogers J et al..  2008.  A novel CpG island set identifies tissue-specific methylation at developmental gene loci.PLoS Biol. 6(1):e22.

Hendrich B, Tweedie S.  2003.  The methyl-CpG binding domain and the evolving role of DNA methylation in animals.Trends Genet. 19(5):269-77.

Hendrich B, Guy J, Ramsahoye B, Wilson V, Bird A.  2001.  Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.Genes Dev. 15(6):710-23.