Leading science, pioneering therapies

CRM Publications

Found 8 results
Filters: Keyword is Cytochrome P-450 Enzyme System  [Clear All Filters]
2013
Medine C.N, Lucendo-Villarin B, Storck C, Wang F, Szkolnicka D, Khan F, Pernagallo S, Black JR, Marriage HM, Ross JA et al..  2013.  Developing high-fidelity hepatotoxicity models from pluripotent stem cells.Stem Cells Transl Med. 2(7):505-9.
2010
Hannoun Z, Fletcher J, Greenhough S, Medine C.N, Samuel K, Sharma R, Pryde A, Black JR, Ross JA, Wilmut I et al..  2010.  The comparison between conditioned media and serum-free media in human embryonic stem cell culture and differentiation.Cell Reprogram. 12(2):133-40.
2001
Rose K, Allan A, Gauldie S, Stapleton G, Dobbie L, Dott K, Martin C, Wang L, Hedlund E, Seckl JR et al..  2001.  Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation.J Biol Chem. 276(26):23937-44.
Bean R, Seckl JR, Lathe R, Martin C.  2001.  Ontogeny of the neurosteroid enzyme Cyp7b in the mouse.Mol Cell Endocrinol. 174(1-2):137-44.
1998
Wolf CR, Campbell SJ, Clark AJ, Smith A, Bishop JO, Henderson CJ.  1998.  The use of transgenic animals to assess the role of metabolism in target organ toxicity.Arch Toxicol Suppl. 20:443-53.
1997
Martin KO, Reiss AB, Lathe R, Javitt NB.  1997.  7 alpha-hydroxylation of 27-hydroxycholesterol: biologic role in the regulation of cholesterol synthesis.J Lipid Res. 38(5):1053-8.
Rose KA, Stapleton G, Dott K, Kieny MP, Best R, Schwarz M, Russell DW, Björkhem I, Seckl JR, Lathe R.  1997.  Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone.Proc Natl Acad Sci U S A. 94(10):4925-30.
Schwarz M, Lund EG, Lathe R, Björkhem I, Russell DW.  1997.  Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.J Biol Chem. 272(38):23995-4001.