CRM Publications

Costa A, Powell LM, Lowell S, Jarman AP.  2017.  Atoh1 in sensory hair cell development: constraints and cofactors.Semin Cell Dev Biol. 65:60-68.

Diffner E, Beck D, Gudgin E, Thoms JAI, Knezevic K, Pridans C, Foster S, Goode D, Lim WKhong, Boelen L et al..  2013.  Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.Blood. 121(12):2289-300.

Zhou X, Smith AG, Waterhouse A, Blin G, Malaguti M, Lin C-Y, Osorno R, Chambers I, Lowell S.  2013.  Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity.Stem Cells. 31(8):1511-22.

Guitart A, Subramani C, Armesilla-Diaz A, Smith G, Sepulveda C, Gezer D, Vukovic M, Dunn K, Pollard P, Holyoake TL et al..  2013.  Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance.Blood. 122(10):1741-5.

Davies OR, Lin C-Y, Radzisheuskaya A, Zhou X, Taube J, Blin G, Waterhouse A, Smith AG, Lowell S.  2013.  Tcf15 primes pluripotent cells for differentiation.Cell Rep. 3(2):472-84.

Spensberger D, Kotsopoulou E, Ferreira R, Broccardo C, Scott LM, Fourouclas N, Ottersbach K, Green AR, Göttgens B.  2012.  Deletion of the Scl +19 enhancer increases the blood stem cell compartment without affecting the formation of mature blood lineages.Exp Hematol. 40(7):588-598.e1.

Stacpoole SRL, Bilican B, Webber DJ, Luzhynskaya A, He XL, Compston A, Karadottir R, ffrench-Constant C, Chandran S.  2011.  Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen.Nat Protoc. 6(8):1229-40.

Tijssen MR, Cvejic A, Joshi A, Hannah RL, Ferreira R, Forrai A, Bellissimo DC, S Oram H, Smethurst PA, Wilson NK et al..  2011.  Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.Dev Cell. 20(5):597-609.

Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MGrazia, Chandran S.  2010.  Cell-mediated neuroprotection in a mouse model of human tauopathy.J Neurosci. 30(30):9973-83.

Göttgens B, Ferreira R, Sanchez M-J, Ishibashi S, Li J, Spensberger D, Lefevre P, Ottersbach K, Chapman M, Kinston S et al..  2010.  cis-Regulatory remodeling of the SCL locus during vertebrate evolution.Mol Cell Biol. 30(24):5741-51.

Wilson NK, Timms RT, Kinston SJ, Cheng Y-H, S Oram H, Landry J-R, Mullender J, Ottersbach K, Göttgens B.  2010.  Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.Mol Cell Biol. 30(15):3853-63.

Bilican B, Fiore-Heriche C, Compston A, Allen ND, Chandran S.  2008.  Induction of Olig2 precursors by FGF involves BMP signalling blockade at the Smad level.PLoS One. 3(8):e2863.

Buscarlet M, Perin A, Laing A, Brickman JM, Stifani S.  2008.  Inhibition of cortical neuron differentiation by Groucho/TLE1 requires interaction with WRPW, but not Eh1, repressor peptides.J Biol Chem. 283(36):24881-8.

Landry J-R, Kinston S, Knezevic K, de Bruijn MFTR, Wilson N, Nottingham WT, Peitz M, Edenhofer F, Pimanda JE, Ottersbach K et al..  2008.  Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver.Blood. 111(6):3005-14.

Pimanda JE, Ottersbach K, Knezevic K, Kinston S, Chan WYI, Wilson NK, Landry J-R, Wood AD, Kolb-Kokocinski A, Green AR et al..  2007.  Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.Proc Natl Acad Sci U S A. 104(45):17692-7.

Gabay L, Lowell S, Rubin LL, Anderson DJ.  2003.  Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro.Neuron. 40(3):485-99.

Carvalho LR, Woods KS, Mendonca BB, Marcal N, Zamparini AL, Stifani S, Brickman JM, Arnhold IJP, Dattani MT.  2003.  A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressor-corepressor interaction.J Clin Invest. 112(8):1192-201.

Brickman JM, Clements M, Tyrell R, McNay D, Woods K, Warner J, Stewart A, Beddington RS, Dattani MT.  2001.  Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders.Development. 128(24):5189-99.

Bucher K, Sofroniew MV, Pannell R, Impey H, Smith AG, Torres EM, Dunnett SB, Jin Y, Baer R, Rabbitts TH.  2000.  The T cell oncogene Tal2 is necessary for normal development of the mouse brain.Dev Biol. 227(2):533-44.