Leading science, pioneering therapies

CRM Publications

Found 4 results
Filters: Keyword is Class I Phosphatidylinositol 3-Kinases  [Clear All Filters]
2009
Al-Qassab H, Smith MA, Irvine EE, Guillermet-Guibert J, Claret M, Choudhury AI, Selman C, Piipari K, Clements M, Lingard S et al..  2009.  Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.Cell Metab. 10(5):343-54.
2008
Graupera M, Guillermet-Guibert J, Foukas LC, Phng L-K, Cain RJ, Salpekar A, Pearce W, Meek S, Millan J, Cutillas PR et al..  2008.  Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.Nature. 453(7195):662-6.
Guillermet-Guibert J, Bjorklof K, Salpekar A, Gonella C, Ramadani F, Bilancio A, Meek S, Smith AG, Okkenhaug K, Vanhaesebroeck B.  2008.  The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.Proc Natl Acad Sci U S A. 105(24):8292-7.
2006
Foukas LC, Claret M, Pearce W, Okkenhaug K, Meek S, Peskett E, Sancho S, Smith AG, Withers DJ, Vanhaesebroeck B.  2006.  Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation.Nature. 441(7091):366-70.