CRM Publications

Lopez-Yrigoyen M, Yang C-T, Fidanza A, Cassetta L, A Taylor H, McCahill A, Sellink E, Von Lindern M, van den Akker E, Mountford JC et al..  2019.  Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.Nat Commun. 10(1):881.

McGarvey AC, Rybtsov S, Souilhol C, Tamagno S, Rice R, Hills D, Godwin D, Rice D, Tomlinson SR, Medvinsky AL.  2017.  A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation.J Exp Med. 214(12):3731-3751.

Mirantes C, Dosil MAlba, Hills D, Yang J, Eritja N, Santacana M, Gatius S, Vilardell F, Medvinsky AL, Matias-Guiu X et al..  2016.  Deletion of Pten in CD45-expressing cells leads to development of T-cell lymphoblastic lymphoma but not myeloid malignancies.Blood. 127(15):1907-11.

Jackson M, Ma R, A Taylor H, Axton RA, Easterbrook J, Kydonaki M, Olivier E, Marenah L, Stanley EG, Elefanty AG et al..  2016.  Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.Stem Cells Transl Med. 5(8):981-90.

Crisan M, Kartalaei PSolaimani, Vink CS, Vink C, Yamada-Inagawa T, Bollerot K, van IJcken W, van der Linden R, Lopes SMChuva de, Monteiro R et al..  2015.  BMP signalling differentially regulates distinct haematopoietic stem cell types.Nat Commun. 6:8040.

Kranc KR, Dzierzak E.  2015.  Relieving oxidative stress in immune cells.J Exp Med. 212(8):1140.

Grover A, Mancini E, Moore S, Mead AJ, Atkinson D, Rasmussen KD, O'Carroll D, Jacobsen SEirik W, Nerlov C.  2014.  Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate.J Exp Med. 211(2):181-8.

Lehwald N, Duhme C, Wildner M, Kuhn S, Fürst G, Forbes SJ, Jonas S, Robson SC, Knoefel WT, Schmelzle M et al..  2014.  HGF and SDF-1-mediated mobilization of CD133+ BMSC for hepatic regeneration following extensive liver resection.Liver Int. 34(1):89-101.

Imanirad P, Kartalaei PSolaimani, Crisan M, Vink C, Yamada-Inagawa T, de Pater E, Kurek D, Kaimakis P, van der Linden R, Speck N et al..  2014.  HIF1α is a regulator of hematopoietic progenitor and stem cell development in hypoxic sites of the mouse embryo.Stem Cell Res. 12(1):24-35.

Diffner E, Beck D, Gudgin E, Thoms JAI, Knezevic K, Pridans C, Foster S, Goode D, Lim WKhong, Boelen L et al..  2013.  Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.Blood. 121(12):2289-300.

Kaimakis P, Crisan M, Dzierzak E.  2013.  The biochemistry of hematopoietic stem cell development.Biochim Biophys Acta. 1830(2):2395-403.

Chevaleyre J, Duchez P, Rodriguez L, Vlaski M, Villacreces A, Conrad-Lapostolle V, Praloran V, Ivanovic Z, de la Grange PBrunet.  2013.  Busulfan administration flexibility increases the applicability of scid repopulating cell assay in NSG mouse model.PLoS One. 8(9):e74361.

Peytour Y, Villacreces A, Chevaleyre J, Ivanovic Z, Praloran V.  2013.  Discarded leukoreduction filters: a new source of stem cells for research, cell engineering and therapy?Stem Cell Res. 11(2):736-42.

Mirshekar-Syahkal B, Haak E, Kimber GM, van Leusden K, Harvey K, O'Rourke J, Laborda J, Bauer SR, de Bruijn MFTR, Ferguson-Smith AC et al..  2013.  Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells.Haematologica. 98(2):163-71.

Guitart A, Subramani C, Armesilla-Diaz A, Smith G, Sepulveda C, Gezer D, Vukovic M, Dunn K, Pollard P, Holyoake TL et al..  2013.  Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance.Blood. 122(10):1741-5.

Gordon-Keylock S, Sobiesiak M, Rybtsov S, Moore K, Medvinsky AL.  2013.  Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs.Blood. 122(14):2338-45.

Corselli M, Chin CJia, Parekh C, Sahaghian A, Wang W, Ge S, Evseenko D, Wang X, Montelatici E, Lazzari L et al..  2013.  Perivascular support of human hematopoietic stem/progenitor cells.Blood. 121(15):2891-901.

Sanjuan-Pla A, Macaulay IC, Jensen CT, Woll PS, Luis TC, Mead AJ, Moore S, Carella C, Matsuoka S, Jones TBouriez et al..  2013.  Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.Nature. 502(7470):232-6.

Malouf C, Ottersbach K.  2013.  The unconventional embryo: immune-restricted potential precedes multipotentiality.Cell Stem Cell. 13(5):509-10.

Spensberger D, Kotsopoulou E, Ferreira R, Broccardo C, Scott LM, Fourouclas N, Ottersbach K, Green AR, Göttgens B.  2012.  Deletion of the Scl +19 enhancer increases the blood stem cell compartment without affecting the formation of mature blood lineages.Exp Hematol. 40(7):588-598.e1.

Buza-Vidas N, Cismasiu VB, Moore S, Mead AJ, Woll PS, Lutteropp M, Melchiori L, Luc S, Bouriez-Jones T, Atkinson D et al..  2012.  Dicer is selectively important for the earliest stages of erythroid development.Blood. 120(12):2412-6.

Luc S, Luis TC, Boukarabila H, Macaulay IC, Buza-Vidas N, Bouriez-Jones T, Lutteropp M, Woll PS, Loughran SJ, Mead AJ et al..  2012.  The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.Nat Immunol. 13(4):412-9.

Jackson M, Axton RA, A Taylor H, Wilson JA, Gordon-Keylock S, Kokkaliaris KD, Brickman JM, Schulz H, Hummel O, Hübner N et al..  2012.  HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche.Stem Cells. 30(2):150-60.

Calaminus SDJ, Guitart A, Guitart A, Sinclair A, Schachtner H, Watson SP, Holyoake TL, Kranc KR, Machesky LM.  2012.  Lineage tracing of Pf4-Cre marks hematopoietic stem cells and their progeny.PLoS One. 7(12):e51361.

Forrester LM, Jackson M.  2012.  Mechanism of action of HOXB4 on the hematopoietic differentiation of embryonic stem cells.Stem Cells. 30(3):379-85.