Leading science, pioneering therapies

CRM Publications

Found 6 results
Filters: Keyword is Steroid Hydroxylases  [Clear All Filters]
2001
Rose K, Allan A, Gauldie S, Stapleton G, Dobbie L, Dott K, Martin C, Wang L, Hedlund E, Seckl JR et al..  2001.  Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation.J Biol Chem. 276(26):23937-44.
Bean R, Seckl JR, Lathe R, Martin C.  2001.  Ontogeny of the neurosteroid enzyme Cyp7b in the mouse.Mol Cell Endocrinol. 174(1-2):137-44.
1997
Martin KO, Reiss AB, Lathe R, Javitt NB.  1997.  7 alpha-hydroxylation of 27-hydroxycholesterol: biologic role in the regulation of cholesterol synthesis.J Lipid Res. 38(5):1053-8.
Rose KA, Stapleton G, Dott K, Kieny MP, Best R, Schwarz M, Russell DW, Björkhem I, Seckl JR, Lathe R.  1997.  Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone.Proc Natl Acad Sci U S A. 94(10):4925-30.
Schwarz M, Lund EG, Lathe R, Björkhem I, Russell DW.  1997.  Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.J Biol Chem. 272(38):23995-4001.
1996
Morley SD, Viard I, Parker KL, Mullins JJ.  1996.  Adrenocortical-specific transgene expression directed by steroid hydroxylase gene promoters.Endocr Res. 22(4):631-9.