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CRM Publications

Found 25 results
Filters: Keyword is Hypertension  [Clear All Filters]
2012
Conway BR, Rennie J, Bailey MA, Dunbar DR, Manning JR, Bellamy CO, Hughes J, Mullins JJ.  2012.  Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy.J Am Soc Nephrol. 23:405–411.
1999
Brosnan MJ, Devlin AM, Clark JS, Mullins JJ, Dominiczak AF.  1999.  Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27.Am J Hypertens. 12(7):724-31.
Jacinto SM, Mullins JJ, Mitchell KD.  1999.  Enhanced renal vascular responsiveness to angiotensin II in hypertensive ren-2 transgenic rats.Am J Physiol. 276(2 Pt 2):F315-22.
Kotelevtsev Y, Brown WR, Fleming S, Kenyon CJ, Edwards CR, Seckl JR, Mullins JJ.  1999.  Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.J Clin Invest. 103(5):683-9.
1998
Montgomery HE, Kiernan LA, Whitworth CE, Fleming S, Unger T, Gohlke P, Mullins JJ, McEwan JR.  1998.  Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27.J Hypertens. 16(5):635-43.
1997
Sharp MG, Kantachuvesiri S, Mullins JJ.  1997.  Genotype and cardiovascular phenotype: lessons from genetically manipulated animals and diseased humans.Curr Opin Nephrol Hypertens. 6(1):51-7.
Mitchell KD, Jacinto SM, Mullins JJ.  1997.  Proximal tubular fluid, kidney, and plasma levels of angiotensin II in hypertensive ren-2 transgenic rats.Am J Physiol. 273(2 Pt 2):F246-53.
1996
Clark AF, Sharp MG, Mullins JJ.  1996.  Gene targeting and its application to basic hypertension research.Clin Sci (Lond). 90(6):435-46.
Mullins LJ, Morley SD, Mullins JJ.  1996.  Transgenics and essential hypertension.J Hum Hypertens. 10(10):627-31.
Véniant M, Ménard J, Bruneval P, Morley S, Gonzales MF, Mullins JJ.  1996.  Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver.J Clin Invest. 98(9):1966-70.
1995
Mitchell KD, Mullins JJ.  1995.  ANG II dependence of tubuloglomerular feedback responsiveness in hypertensive ren-2 transgenic rats.Am J Physiol. 268(5 Pt 2):F821-8.
Véniant M, Whitworth CE, Ménard J, Sharp MG, Gonzales MF, Bruneval P, Mullins JJ.  1995.  Developmental studies demonstrate age-dependent elevation of renin activity in TGR(mRen2)27 rats.Am J Hypertens. 8(12 Pt 1):1167-76.
Whitworth CE, Veniant MM, Firth JD, Cumming AD, Mullins JJ.  1995.  Endothelin in the kidney in malignant phase hypertension.Hypertension. 26(6 Pt 1):925-31.
Gardiner SM, March JE, Kemp PA, Mullins JJ, Bennett T.  1995.  Haemodynamic effects of losartan and the endothelin antagonist, SB 209670, in conscious, transgenic ((mRen-2)27), hypertensive rats.Br J Pharmacol. 116(4):2237-44.
1994
Mullins JJ, Mullins LJ.  1994.  Transgenes, hypotheses, and hypertension.Hypertension. 23(4):428-30.
1993
Unger T, Ganten D, Johnston CI, Lever AF, Mullins JJ, Sassard J, van Zwieten PA.  1993.  Round table 1. Do transgenic techniques help us to understand hypertension?J Hypertens Suppl. 11(5):S374-9.
Brosnan MJ, Mullins JJ.  1993.  Transgenic animals in hypertension and cardiovascular research.Exp Nephrol. 1(1):3-12.
1992
Kimura S, Mullins JJ, Bunnemann B, Metzger R, Hilgenfeldt U, Zimmermann F, Jacob H, Fuxe K, Ganten D, Kaling M.  1992.  High blood pressure in transgenic mice carrying the rat angiotensinogen gene.EMBO J. 11(3):821-7.
Sander M, Bader M, Djavidani B, Maser-Gluth C, Vecsei P, Mullins JJ, Ganten D, Peters J.  1992.  The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27.Endocrinology. 131(2):807-14.
Barrett GL, Mullins JJ.  1992.  Strategies towards a transgenic model of essential hypertension.Biochem Pharmacol. 43(5):925-30.
Barrett GL, Mullins JJ.  1992.  Studies on blood pressure regulation in hypertensive ren-2 transgenic rats.Kidney Int Suppl. 37:S125-8.
Barrett G, Mullins JJ.  1992.  Transgenic animal models of cardiovascular disease.Curr Opin Biotechnol. 3(6):637-40.
Bachmann S, Peters J, Engler E, Ganten D, Mullins JJ.  1992.  Transgenic rats carrying the mouse renin gene--morphological characterization of a low-renin hypertension model.Kidney Int. 41(1):24-36.
1991
Ganten D, Takahashi S, Lindpaintner K, Mullins JJ.  1991.  Genetic basis of hypertension. The renin-angiotensin paradigm.Hypertension. 18(5 Suppl):III109-14.
Ganten D, Lindpaintner K, Ganten U, Peters J, Zimmermann F, Bader M, Mullins JJ.  1991.  Transgenic rats: new animal models in hypertension research. Invited lecture.Hypertension. 17(6 Pt 2):843-55.