Leading science, pioneering therapies

CRM Publications

Found 25 results
Filters: Keyword is Genetic Vectors  [Clear All Filters]
2014
Brown TI, Collie DS, Shaw DJ, Rzechorzek NM, Sallenave J-M.  2014.  Sheep lung segmental delivery strategy demonstrates adenovirus priming of local lung responses to bacterial LPS and the role of elafin as a response modulator.PLoS One. 9(9):e107590.
van Gestel MA, van Erp S, Sanders LE, Brans MAD, Luijendijk MCM, Merkestein M, Pasterkamp RJ, Adan RAH.  2014.  shRNA-induced saturation of the microRNA pathway in the rat brain.Gene Ther. 21(2):205-11.
2011
Barakat TStefan, Gunhanlar N, Pardo CGontan, Achame EMulugeta, Ghazvini M, Boers R, Kenter A, Rentmeester E, J Grootegoed A, Gribnau J.  2011.  RNF12 activates Xist and is essential for X chromosome inactivation.PLoS Genet. 7(1):e1002001.
2010
Mira H, Andreu Z, Suh H, D Lie C, Jessberger S, Consiglio A, San Emeterio J, Hortigüela R, M Marqués-Torrejón Á, Nakashima K et al..  2010.  Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus.Cell Stem Cell. 7(1):78-89.
Brickman JM, Tsakiridis A, To C, Stanford WL.  2010.  A wider context for gene trap mutagenesis.Methods Enzymol. 477:271-95.
2009
Tsakiridis A, Tzouanacou E, Rahman A, Colby D, Axton RA, Chambers I, Wilson V, Forrester LM, Brickman JM.  2009.  Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells.Nucleic Acids Res. 37(19):e129.
Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, Cowling R, Wang W, Liu P, Gertsenstein M et al..  2009.  piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells.Nature. 458(7239):766-70.
Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K.  2009.  Virus-free induction of pluripotency and subsequent excision of reprogramming factors.Nature. 458(7239):771-5.
2007
Tsakiridis A, Tzouanacou E, Larralde O, Watts TM, Wilson V, Forrester LM, Brickman JM.  2007.  A novel triple fusion reporter system for use in gene trap mutagenesis.Genesis. 45(6):353-60.
2006
Mee PJ, O'Brien CM, Thomson H, van der Sar S, Lakics V, Allsopp TE.  2006.  Embryonic stem cells as a source of differentiated neural cells for pharmacological screens.Methods Mol Biol. 329:353-69.
2005
Kelly K, Hutchinson G, Nebenuis-Oosthuizen D, Smith AG, Bartsch JW, Horiuchi K, Rittger A, Manova K, Docherty AJP, Blobel CP.  2005.  Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice.Dev Dyn. 232(1):221-31.
2004
Garrick D, Samara V, McDowell TL, Smith AG, Dobbie L, Higgs DR, Gibbons RJ.  2004.  A conserved truncated isoform of the ATR-X syndrome protein lacking the SWI/SNF-homology domain.Gene. 326:23-34.
Henriksen PA, Devitt A, Kotelevtsev Y, Sallenave J-M.  2004.  Gene delivery of the elastase inhibitor elafin protects macrophages from neutrophil elastase-mediated impairment of apoptotic cell recognition.FEBS Lett. 574(1-3):80-4.
2003
Ferrell WR, Lockhart JC, Kelso EB, Dunning L, Plevin R, Meek SE, Smith AG, Hunter GD, McLean JS, McGarry F et al..  2003.  Essential role for proteinase-activated receptor-2 in arthritis.J Clin Invest. 111(1):35-41.
2001
Lowell S, Watt FM.  2001.  Delta regulates keratinocyte spreading and motility independently of differentiation.Mech Dev. 107(1-2):133-40.
2000
Shen MH, Mee PJ, Nichols J, Yang J, Brook F, Gardner RL, Smith AG, Brown WR.  2000.  A structurally defined mini-chromosome vector for the mouse germ line.Curr Biol. 10(1):31-4.
1998
Loupart ML, Shen MH, Smith A.  1998.  Differential stability of a human mini-chromosome in mouse cell lines.Chromosoma. 107(4):255-9.
McClive P, Pall G, Newton K, Lee M, Mullins JJ, Forrester LM.  1998.  Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector.Dev Dyn. 212(2):267-76.
1997
Rose KA, Stapleton G, Dott K, Kieny MP, Best R, Schwarz M, Russell DW, Björkhem I, Seckl JR, Lathe R.  1997.  Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone.Proc Natl Acad Sci U S A. 94(10):4925-30.
Ramage AD, Clark AJ, Smith AG, Mountford P, Burt DW.  1997.  Improved EBV-based shuttle vector system: dicistronic mRNA couples the synthesis of the Epstein-Barr nuclear antigen-1 protein to neomycin resistance.Gene. 197(1-2):83-9.
1996
Clark AF, Sharp MG, Mullins JJ.  1996.  Gene targeting and its application to basic hypertension research.Clin Sci (Lond). 90(6):435-46.
Forrester LM, Nagy A, Sam M, Watt A, Stevenson L, Bernstein A, Joyner AL, Wurst W.  1996.  An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro.Proc Natl Acad Sci U S A. 93(4):1677-82.
1995
Smith AG, De Sousa MA, Kwabi-Addo B, Heppell-Parton A, Impey H, Rabbitts P.  1995.  A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.Nat Genet. 9(4):376-85.
1990
Savatier P, Morgenstern J, Beddington RS.  1990.  Permissiveness to murine leukemia, virus expression during preimplantation and early postimplantation mouse development.Development. 109(3):655-65.