CRM Publications

Livigni A, Brickman JM.  2013.  Oct4: the final frontier, differentiation defining pluripotency.Dev Cell. 25(6):547-8.

Wongtawan T, Taylor JE, Lawson KA, Wilmut I, Pennings S.  2011.  Histone H4K20me3 and HP1α are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells.J Cell Sci. 124(Pt 11):1878-90.

Anderson RA, Bayne R, Gardner J, de Sousa P.  2010.  Brain-derived neurotrophic factor is a regulator of human oocyte maturation and early embryo development.Fertil Steril. 93(5):1394-406.

Meek S, Buehr M, Sutherland L, Thomson AJ, Mullins JJ, Smith AG, Burdon T.  2010.  Efficient gene targeting by homologous recombination in rat embryonic stem cells.PLoS One. 5(12):e14225.

Canham MA, Sharov AA, Ko MSH, Brickman JM.  2010.  Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript.PLoS Biol. 8(5):e1000379.

de Sousa P, Gardner J, Sneddon S, Pells S, Tye BJorgensen, Dand P, Collins DM, Stewart K, Shaw L, Przyborski S et al..  2009.  Clinically failed eggs as a source of normal human embryo stem cells.Stem Cell Res. 2(3):188-97.

Taylor J, Moore H, Beaujean N, Gardner J, Wilmut I, Meehan R, Young L.  2009.  Cloning and expression of sheep DNA methyltransferase 1 and its development-specific isoform.Mol Reprod Dev. 76(5):501-13.

Silva J, Nichols J, Theunissen TW, Guo G, van Oosten AL, Barrandon O, Wray J, Yamanaka S, Chambers I, Smith A.  2009.  Nanog is the gateway to the pluripotent ground state.Cell. 138(4):722-37.

Kaji K, Nichols J, Hendrich B.  2007.  Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.Development. 134(6):1123-32.

Nichols J, Ying Q-L.  2006.  Derivation and propagation of embryonic stem cells in serum- and feeder-free culture.Methods Mol Biol. 329:91-8.

Munsie M, Mountford P, Nichols J.  2006.  Transgenic systems in nuclear reprogramming.Methods Mol Biol. 325:115-28.

Smith A.  2005.  The battlefield of pluripotency.Cell. 123(5):757-60.

Kunath T, Arnaud D, Uy GD, Okamoto I, Chureau C, Yamanaka Y, Heard E, Gardner RL, Avner P, Rossant J.  2005.  Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts.Development. 132(7):1649-61.

Jackson M, Baird JW, Nichols J, Wilkie R, Ansell JD, Graham GJ, Forrester LM.  2003.  Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.Dev Dyn. 228(4):740-4.

Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S, Smith A.  2003.  Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells.Cell. 113(5):643-55.

Buehr M, Nichols J, Stenhouse FH, Mountford P, Greenhalgh CJ, Kantachuvesiri S, Brooker G, Mullins JJ, Smith AG.  2003.  Rapid loss of Oct-4 and pluripotency in cultured rodent blastocysts and derivative cell lines.Biol Reprod. 68(1):222-9.

Ying Q-L, Nichols J, Evans EP, Smith AG.  2002.  Changing potency by spontaneous fusion.Nature. 416(6880):545-8.

Nichols J, Chambers I, Taga T, Smith A.  2001.  Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines.Development. 128(12):2333-9.

O'Carroll D, Erhardt S, Pagani M, Barton SC, Surani MA, Jenuwein T.  2001.  The polycomb-group gene Ezh2 is required for early mouse development.Mol Cell Biol. 21(13):4330-6.

Nichols J, Chambers I, Smith A.  1994.  Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor.Exp Cell Res. 215(1):237-9.

Yoshida K, Chambers I, Nichols J, Smith A, Saito M, Yasukawa K, Shoyab M, Taga T, Kishimoto T.  1994.  Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways.Mech Dev. 45(2):163-71.

Savatier P, Morgenstern J, Beddington RS.  1990.  Permissiveness to murine leukemia, virus expression during preimplantation and early postimplantation mouse development.Development. 109(3):655-65.