Leading science, pioneering therapies

Thymus generation and regeneration group publications

2009

Lippuner C, Paape D, Paterou A, Brand J, Richardson M, Smith AG, Hoffmann K, Brinkmann V, C Blackburn C, Aebischer T.  2009.  Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice.FASEB J. 23(2):483-91.
Sheridan JM, Taoudi S, Medvinsky AL, C Blackburn C.  2009.  A novel method for the generation of reaggregated organotypic cultures that permits juxtaposition of defined cell populations.Genesis. 47(5):346-51.

2008

Foster K, Sheridan JM, Veiga-Fernandes H, Roderick K, Pachnis V, Adams R, C Blackburn C, Kioussis D, Coles M.  2008.  Contribution of neural crest-derived cells in the embryonic and adult thymus.J Immunol. 180(5):3183-9.
Taoudi S, le Gonneau C, Moore K, Sheridan JM, C Blackburn C, Taylor E, Medvinsky AL.  2008.  Extensive hematopoietic stem cell generation in the AGM region via maturation of VE-cadherin+CD45+ pre-definitive HSCs.Cell Stem Cell. 3(1):99-108.
Depreter MGL, Blair NF, Gaskell TL, Nowell CS, Davern K, Pagliocca A, Stenhouse FH, Farley A, Fraser A, Vrana J et al..  2008.  Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells.Proc Natl Acad Sci U S A. 105(3):961-6.

2007

Nowell CS, Farley A, C Blackburn C.  2007.  Thymus organogenesis and development of the thymic stroma.Methods Mol Biol. 380:125-62.
DeMonte L, Porcellini S, Tafi E, Sheridan JM, Gordon J, Depreter MGL, Blair NF, Panigada M, Sanvito F, Merati B et al..  2007.  EVA regulates thymic stromal organisation and early thymocyte development.Biochem Biophys Res Commun. 356(2):334-40.

2006

Morris L, Gordon J, C Blackburn C.  2006.  Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.Mamm Genome. 17(2):178-87.
Patel SR, Gordon J, Mahbub F, C Blackburn C, Manley NR.  2006.  Bmp4 and Noggin expression during early thymus and parathyroid organogenesis.Gene Expr Patterns. 6(8):794-9.

2005

Gomez-Escobar N, Bennett CL, Prieto-Lafuente L, Aebischer T, C Blackburn C, Maizels RM.  2005.  Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function.BMC Biol. 3:8.
Gordon J, Wilson V, Moore-Scott BA, Manley NR, C Blackburn C.  2005.  In vivo and in vitro assays of thymic organogenesis.Methods Mol Med. 105:303-10.
Aebischer T, Bennett CL, Pelizzola M, Vizzardelli C, Pavelka N, Urbano M, Capozzoli M, Luchini A, Ilg T, Granucci F et al..  2005.  A critical role for lipophosphoglycan in proinflammatory responses of dendritic cells to Leishmania mexicana.Eur J Immunol. 35(2):476-86.

2004

Gordon J, Wilson V, Blair NF, Sheridan JM, Farley A, Wilson L, Manley NR, C Blackburn C.  2004.  Functional evidence for a single endodermal origin for the thymic epithelium.Nat Immunol. 5(5):546-53.
C Blackburn C, Manley NR.  2004.  Developing a new paradigm for thymus organogenesis.Nat Rev Immunol. 4(4):278-89.

2003

Moore-Scott BA, Gordon J, C Blackburn C, Condie BGene, Manley NR.  2003.  New serum-free in vitro culture technique for midgestation mouse embryos.Genesis. 35(3):164-8.
Bennett CL, Colledge L, Richards HE, Reay PA, C Blackburn C, Aebischer T.  2003.  Uncompromised generation of a specific H-2DM-dependent peptide-MHC class II complex from exogenous antigen in Leishmania mexicana-infected dendritic cells.Eur J Immunol. 33(12):3504-13.

2002

2001

Bennett CL, Misslitz A, Colledge L, Aebischer T, C Blackburn C.  2001.  Silent infection of bone marrow-derived dendritic cells by Leishmania mexicana amastigotes.Eur J Immunol. 31(3):876-83.
C Blackburn C, Grogan JL, Augustine CL, Miller JF, Varigos G, Morahan G.  2001.  Effect of localized cytokine dysregulation: accelerated rejection of IL-2-expressing skin grafts.Immunol Cell Biol. 79(2):128-31.

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