Leading science, pioneering therapies

RNA function in germ and stem cell biology group publications

2012

Wang D, Zhang Z, O'Loughlin E, Lee T, Houel S, O'Carroll D, Tarakhovsky A, Ahn NG, Yi R.  2012.  Quantitative functions of Argonaute proteins in mammalian development.Genes Dev. 26(7):693-704.
Mancini E, Sanjuan-Pla A, Luciani L, Moore S, Grover A, Zay A, Rasmussen KD, Luc S, Bilbao D, O'Carroll D et al..  2012.  FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors.EMBO J. 31(2):351-65.

2011

Muncan V, Heijmans J, Krasinski SD, Büller NV, Wildenberg ME, Meisner S, Radonjic M, Stapleton KA, Lamers WH, Biemond I et al..  2011.  Blimp1 regulates the transition of neonatal to adult intestinal epithelium.Nat Commun. 2:452.
De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D.  2011.  The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements.Nature. 480(7376):259-63.

2010

Rasmussen KD, Simmini S, Abreu-Goodger C, Bartonicek N, Di Giacomo M, Bilbao-Cortes D, Horos R, Von Lindern M, Enright AJ, O'Carroll D.  2010.  The miR-144/451 locus is required for erythroid homeostasis.J Exp Med. 207(7):1351-8.
Hanina SA, Mifsud W, Down TA, Hayashi K, O'Carroll D, Lao K, Miska EA, M Surani A.  2010.  Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.PLoS Genet. 6(10):e1001163.
Andersson T, Rahman S, Sansom SN, Alsiö JM, Kaneda M, Smith J, O'Carroll D, Tarakhovsky A, Livesey FJ.  2010.  Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs.PLoS One. 5(10):e13453.
Schaefer A, Im H-I, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny PJ, O'Carroll D, Greengard P.  2010.  Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.J Exp Med. 207(9):1843-51.
Yang J-S, Maurin T, Robine N, Rasmussen KD, Jeffrey KL, Chandwani R, Papapetrou EP, Sadelain M, O'Carroll D, Lai EC.  2010.  Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis.Proc Natl Acad Sci U S A. 107(34):15163-8.

2009

Yi R, H Pasolli A, Landthaler M, Hafner M, Ojo T, Sheridan R, Sander C, O'Carroll D, Stoffel M, Tuschl T et al..  2009.  DGCR8-dependent microRNA biogenesis is essential for skin development.Proc Natl Acad Sci U S A. 106(2):498-502.
Kaneda M, Tang F, O'Carroll D, Lao K, M Surani A.  2009.  Essential role for Argonaute2 protein in mouse oogenesis.Epigenetics Chromatin. 2(1):9.

2008

Liston A, Lu L-F, O'Carroll D, Tarakhovsky A, Rudensky AY.  2008.  Dicer-dependent microRNA pathway safeguards regulatory T cell function.J Exp Med. 205(9):1993-2004.
Tang F, Hajkova P, O'Carroll D, Lee C, Tarakhovsky A, Lao K, M Surani A.  2008.  MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo.Biochem Biophys Res Commun. 372(1):24-9.
Hayashi K, Lopes SMChuva de, Kaneda M, Tang F, Hajkova P, Lao K, O'Carroll D, Das PP, Tarakhovsky A, Miska EA et al..  2008.  MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.PLoS One. 3(3):e1738.

2007

Schaefer A, O'Carroll D, Tan CLek, Hillman D, Sugimori M, Llinas R, Greengard P.  2007.  Cerebellar neurodegeneration in the absence of microRNAs.J Exp Med. 204(7):1553-8.
Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Y Sun A, Lee C, Tarakhovsky A, Lao K, M Surani A.  2007.  Maternal microRNAs are essential for mouse zygotic development.Genes Dev. 21(6):644-8.
O'Carroll D, Mecklenbrauker I, Das PPratim, Santana A, Koenig U, Enright AJ, Miska EA, Tarakhovsky A.  2007.  A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway.Genes Dev. 21(16):1999-2004.

2006

Tang F, Hajkova P, Barton SC, O'Carroll D, Lee C, Lao K, M Surani A.  2006.  220-plex microRNA expression profile of a single cell.Nat Protoc. 1(3):1154-9.
Ohinata Y, Seki Y, Payer B, O'Carroll D, Surani MA, Saitou M.  2006.  Germline recruitment in mice: a genetic program for epigenetic reprogramming.Ernst Schering Res Found Workshop. (60):143-74.

Pages