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Pluripotent stem cell differentiation group publications

2019

Narraway C, Davis O, Lowell S, Lythgoe KA, Turner SJ, Marshall S.  2019.  Biotic analogies for self-organising cities
Punovuori K, Migueles RPortero, Malaguti M, Blin G, Macleod K, Carragher NO, Pieters T, van Roy F, Stemmler MP, Lowell S.  2019.  N-cadherin stabilises neural identity by dampening anti-neural signals
Blin G, Sadurska D, Migueles RPortero, Chen N, Watson JA, Lowell S.  2019.  Nessys: A new set of tools for the automated detection of nuclei within intact tissues and dense 3D cultures.PLoS Biol. 17(8):e3000388.

2018

Blin G, Wisniewski D, Picart C, Théry M, Puceat M, Lowell S.  2018.  Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells.Development. 145(18)
Row RH, Pegg A, Kinney BA, Farr GH, Maves L, Lowell S, Wilson V, Martin BL.  2018.  BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity.Elife. 7

2017

Costa A, Powell LM, Lowell S, Jarman AP.  2017.  Atoh1 in sensory hair cell development: constraints and cofactors.Semin Cell Dev Biol. 65:60-68.
Burute M, Prioux M, Blin G, Truchet S, Letort G, Tseng Q, Bessy T, Lowell S, Young J, Filhol O et al..  2017.  Polarity Reversal by Centrosome Repositioning Primes Cell Scattering during Epithelial-to-Mesenchymal Transition.Dev Cell. 40(2):168-184.

2016

Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S et al..  2016.  Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons.Elife. 5

2015

Laing AF, Lowell S, Brickman JM.  2015.  Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression.Dev Biol. 397(1):56-66.

2014

Tsakiridis A, Huang Y, Blin G, Skylaki S, Wymeersch FJ, Osorno R, Economou C, Karagianni E, Zhao S, Lowell S et al..  2014.  Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors.Development. 141(6):1209-21.

2013

Huang C, Jackson M, Samuel K, A Taylor H, Lowell S, Forrester LM.  2013.  Haematopoietic differentiation is inhibited when Notch activity is enhanced in FLK1(+) mesoderm progenitors.Stem Cell Res. 11(3):1273-87.
Lowell S.  2013.  Getting the measure of things: the physical biology of stem cells.Development. 140(20):4125-8.
Malaguti M, Nistor PA, Blin G, Pegg A, Zhou X, Lowell S.  2013.  Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin.Elife. 2:e01197.
Davies OR, Lin C-Y, Radzisheuskaya A, Zhou X, Taube J, Blin G, Waterhouse A, Smith AG, Lowell S.  2013.  Tcf15 primes pluripotent cells for differentiation.Cell Rep. 3(2):472-84.
Zhou X, Smith AG, Waterhouse A, Blin G, Malaguti M, Lin C-Y, Osorno R, Chambers I, Lowell S.  2013.  Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity.Stem Cells. 31(8):1511-22.

2012

Boulter L, Govaere O, Bird TG, Radulescu S, Ramachandran P, Pellicoro A, Ridgway RA, Seo SSoo, Spee B, van Rooijen N et al..  2012.  Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.Nat Med. 18(4):572-9.

2006

Lowell S, Benchoua A, Heavey B, Smith AG.  2006.  Notch promotes neural lineage entry by pluripotent embryonic stem cells.PLoS Biol. 4(5):e121.
Lowell S.  2006.  Stem cells in the genomic age.Genome Biol. 7(5):315.

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