Leading science, pioneering therapies

Myelination and repair in the CNS group publications

2012

Jarjour AA, Zhang H, Bauer N, ffrench-Constant C, Williams AC.  2012.  In vitro modeling of central nervous system myelination and remyelination.Glia. 60(1):1-12.
Eva R, Crisp S, Marland JRK, Norman JC, Kanamarlapudi V, ffrench-Constant C, Fawcett JW.  2012.  ARF6 directs axon transport and traffic of integrins and regulates axon growth in adult DRG neurons.J Neurosci. 32(30):10352-64.
Franklin RJM, ffrench-Constant C, Edgar JM, Smith KJ.  2012.  Neuroprotection and repair in multiple sclerosis.Nat Rev Neurol. 8(11):624-34.

2011

Stacpoole SRL, Bilican B, Webber DJ, Luzhynskaya A, He XL, Compston A, Karadottir R, ffrench-Constant C, Chandran S.  2011.  Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen.Nat Protoc. 6(8):1229-40.
Laursen LS, Chan CW, ffrench-Constant C.  2011.  Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K.J Cell Biol. 192(5):797-811.
Huang JK, Fancy SPJ, Zhao C, Rowitch DH, ffrench-Constant C, Franklin RJM.  2011.  Myelin regeneration in multiple sclerosis: targeting endogenous stem cells.Neurotherapeutics. 8(4):650-8.
Sprooten E, Sussmann JE, Moorhead TW, Whalley HC, ffrench-Constant C, Blumberg HP, Bastin ME, Hall J, Lawrie SM, McIntosh AM.  2011.  Association of white matter integrity with genetic variation in an exonic DISC1 SNP.Mol Psychiatry. 16(7):685,688-9.
Huang JK, Jarjour AA, ffrench-Constant C, Franklin RJM.  2011.  Retinoid X receptors as a potential avenue for regenerative medicine in multiple sclerosis.Expert Rev Neurother. 11(4):467-8.
Almeida RG, Czopka T, ffrench-Constant C, Lyons DA.  2011.  Individual axons regulate the myelinating potential of single oligodendrocytes in vivo.Development. 138(20):4443-50.
Huang JK, Jarjour AA, Oumesmar BNait, Kerninon C, Williams AC, Krezel W, Kagechika H, Bauer J, Zhao C, Van Evercooren ABaron- et al..  2011.  Retinoid X receptor gamma signaling accelerates CNS remyelination.Nat Neurosci. 14(1):45-53.
Tan CLik, Kwok JCF, Patani R, ffrench-Constant C, Chandran S, Fawcett JW.  2011.  Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling.J Neurosci. 31(17):6289-95.
Kazanis I, ffrench-Constant C.  2011.  Extracellular matrix and the neural stem cell niche.Dev Neurobiol. 71(11):1006-17.

2010

Afshari FT, Kwok JC, Andrews MR, Blits B, Martin KR, Faissner A, ffrench-Constant C, Fawcett JW.  2010.  Integrin activation or alpha 9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration.Brain. 133(Pt 2):448-64.
Vesterinen HM, Sena ES, ffrench-Constant C, Williams AC, Chandran S, Macleod MR.  2010.  Improving the translational hit of experimental treatments in multiple sclerosis.Mult Scler. 16(9):1044-55.
Franklin RJM, ffrench-Constant C.  2010.  Stem cell treatments and multiple sclerosis.BMJ. 340:c1387.
Eva R, Dassie E, Caswell PT, Dick G, ffrench-Constant C, Norman JC, Fawcett JW.  2010.  Rab11 and its effector Rab coupling protein contribute to the trafficking of beta 1 integrins during axon growth in adult dorsal root ganglion neurons and PC12 cells.J Neurosci. 30(35):11654-69.
Marthiens V, Kazanis I, Moss L, Long K, ffrench-Constant C.  2010.  Adhesion molecules in the stem cell niche--more than just staying in shape?J Cell Sci. 123(Pt 10):1613-22.
Czopka T, Von Holst A, ffrench-Constant C, Faissner A.  2010.  Regulatory mechanisms that mediate tenascin C-dependent inhibition of oligodendrocyte precursor differentiation.J Neurosci. 30(37):12310-22.

Pages