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Mesoderm and haematopoietic differentiation group publications

2012

Zhuang L, Pound JD, Willems JJLP, A Taylor H, Forrester LM, Gregory CD.  2012.  Pure populations of murine macrophages from cultured embryonic stem cells. Application to studies of chemotaxis and apoptotic cell clearance.J Immunol Methods. 385(1-2):1-14.
Jackson M, Axton RA, A Taylor H, Wilson JA, Gordon-Keylock S, Kokkaliaris KD, Brickman JM, Schulz H, Hummel O, Hübner N et al..  2012.  HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche.Stem Cells. 30(2):150-60.

2010

Gordon-Keylock S, Jackson M, Huang C, Samuel K, Axton RA, Oostendorp RAJ, A Taylor H, Wilson J, Forrester LM.  2010.  Induction of hematopoietic differentiation of mouse embryonic stem cells by an AGM-derived stromal cell line is not further enhanced by overexpression of HOXB4.Stem Cells Dev. 19(11):1687-98.
Jackson M, A Taylor H, Jones EA, Forrester LM.  2010.  The culture of mouse embryonic stem cells and formation of embryoid bodies.Methods Mol Biol. 633:1-18.

2009

Schulz H, Kolde R, Adler P, Aksoy I, Anastassiadis K, Bader M, Billon N, Boeuf H, Bourillot P-Y, Buchholz F et al..  2009.  The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.PLoS One. 4(9):e6804.
Tsakiridis A, Tzouanacou E, Rahman A, Colby D, Axton RA, Chambers I, Wilson V, Forrester LM, Brickman JM.  2009.  Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells.Nucleic Acids Res. 37(19):e129.

2008

Axton RA, Wallis JA, A Taylor H, Hanks M, Forrester LM.  2008.  Aminopeptidase O contains a functional nucleolar localization signal and is implicated in vascular biology.J Cell Biochem. 103(4):1171-82.
Ledran MH, Krassowska A, Armstrong L, Dimmick I, Renström J, Lang R, Yung S, Santibanez-Coref M, Dzierzak E, Stojkovic M et al..  2008.  Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.Cell Stem Cell. 3(1):85-98.

2007

Tsakiridis A, Tzouanacou E, Larralde O, Watts TM, Wilson V, Forrester LM, Brickman JM.  2007.  A novel triple fusion reporter system for use in gene trap mutagenesis.Genesis. 45(6):353-60.

2006

Jackson M, Watt AJ, Gautier P, Gilchrist D, Driehaus J, Graham GJ, Keebler J, Prugnolle F, Awadalla P, Forrester LM.  2006.  A murine specific expansion of the Rhox cluster involved in embryonic stem cell biology is under natural selection.BMC Genomics. 7:212.
Watt AJ, Forrester LM.  2006.  Deriving and identifying hepatocytes from embryonic stem cells.Stem Cell Rev. 2(1):19-22.
Bashamboo A, A Taylor H, Samuel K, Panthier J-J, Whetton AD, Forrester LM.  2006.  The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway.J Cell Sci. 119(Pt 15):3039-46.
Krassowska A, Gordon-Keylock S, Samuel K, Gilchrist D, Dzierzak E, Oostendorp R, Forrester LM, Ansell JD.  2006.  Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad-mesonephros microenvironment.Exp Cell Res. 312(18):3595-603.

2005

Macpherson H, Keir P, Webb S, Samuel K, Boyle S, Bickmore WA, Forrester LM, Dorin J.  2005.  Bone marrow-derived SP cells can contribute to the respiratory tract of mice in vivo.J Cell Sci. 118(Pt 11):2441-50.

2004

Jackson M, Krassowska A, Gilbert N, Chevassut T, Forrester LM, Ansell JD, Ramsahoye B.  2004.  Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.Mol Cell Biol. 24(20):8862-71.
Pall GS, Wallis J, Axton RA, Brownstein DG, Gautier P, Buerger K, Mulford C, Mullins JJ, Forrester LM.  2004.  A novel transmembrane MSP-containing protein that plays a role in right ventricle development.Genomics. 84(6):1051-9.

2003

Newsome PN, Johannessen I, Boyle S, Dalakas E, McAulay KA, Samuel K, Rae F, Forrester LM, Turner ML, Hayes PC et al..  2003.  Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion.Gastroenterology. 124(7):1891-900.
Jackson M, Baird JW, Nichols J, Wilkie R, Ansell JD, Graham GJ, Forrester LM.  2003.  Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.Dev Dyn. 228(4):740-4.

2002

Jackson M, Baird JW, Cambray N, Ansell JD, Forrester LM, Graham GJ.  2002.  Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.J Biol Chem. 277(41):38683-92.

2001

Watt AJ, Jones EA, Ure JM, Peddie D, Wilson DI, Forrester LM.  2001.  A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm.Mech Dev. 100(2):205-15.

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