Leading science, pioneering therapies

Liver stem cells and regeneration group publications

2012

Forbes SJ, Newsome PN.  2012.  New horizons for stem cell therapy in liver disease.J Hepatol. 56(2):496-9.

2011

Kallis YN, Robson AJ, Fallowfield JA, Thomas HC, Alison MR, Wright NA, Goldin RD, Iredale JP, Forbes SJ.  2011.  Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response.Gut. 60(4):525-33.
Schrader J, Gordon-Walker TT, Aucott RL, Van Deemter M, Quaas A, Walsh S, Benten D, Forbes SJ, Wells RG, Iredale JP.  2011.  Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells.Hepatology. 53(4):1192-205.
Payne C, Samuel K, Pryde A, King J, Brownstein D, Schrader J, Medine C.N, Forbes SJ, Iredale JP, Newsome PN et al..  2011.  Persistence of functional hepatocyte-like cells in immune-compromised mice.Liver Int. 31(2):254-62.
Forbes SJ, Parola M.  2011.  Liver fibrogenic cells.Best Pract Res Clin Gastroenterol. 25(2):207-17.
Hay DC, Pernagallo S, Diaz-Mochon JJose, Medine C.N, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D et al..  2011.  Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.Stem Cell Res. 6(2):92-102.
Gibbons MA, Mackinnon AC, Ramachandran P, Dhaliwal K, Duffin R, Phythian-Adams AT, van Rooijen N, Haslett C, Howie SE, A Simpson J et al..  2011.  Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis.Am J Respir Crit Care Med. 184(5):569-81.
Thomas JA, Pope C, Wojtacha D, Robson AJ, Gordon-Walker TT, Hartland SN, Ramachandran P, Van Deemter M, Hume DA, Iredale JP et al..  2011.  Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function.Hepatology. 53(6):2003-15.

2010

Kung JWC, Currie IS, Forbes SJ, Ross JA.  2010.  Liver development, regeneration, and carcinogenesis.J Biomed Biotechnol. 2010:984248.
Terrace JD, Hay DC, Samuel K, Anderson RA, Currie IS, Parks RW, Forbes SJ, Ross JA.  2010.  Portal venous endothelium in developing human liver contains haematopoietic and epithelial progenitor cells.Exp Cell Res. 316(9):1637-47.
Sullivan G, Hay DC, Park I-H, Fletcher J, Hannoun Z, Payne C, Dalgetty D, Black JR, Ross JA, Samuel K et al..  2010.  Generation of functional human hepatic endoderm from human induced pluripotent stem cells.Hepatology. 51(1):329-35.
Lorenzini S, Bird TG, Boulter L, Bellamy C, Samuel K, Aucott RL, Clayton E, Andreone P, Bernardi M, Golding M et al..  2010.  Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver.Gut. 59(5):645-54.
Stutchfield BM, Rashid S, Forbes SJ, Wigmore SJ.  2010.  Practical barriers to delivering autologous bone marrow stem cell therapy as an adjunct to liver resection.Stem Cells Dev. 19(2):155-62.
Stutchfield BM, Forbes SJ, Wigmore SJ.  2010.  Prospects for stem cell transplantation in the treatment of hepatic disease.Liver Transpl. 16(7):827-36.

2009

Kallis YN, Forbes SJ.  2009.  The bone marrow and liver fibrosis: friend or foe?Gastroenterology. 137(4):1218-21.
Kung JWC, Forbes SJ.  2009.  Stem cells and liver repair.Curr Opin Biotechnol. 20(5):568-74.
Terrace JD, Hay DC, Samuel K, Payne C, Anderson RA, Currie IS, Parks RW, Forbes SJ, Ross JA.  2009.  Side population cells in developing human liver are primarily haematopoietic progenitor cells.Exp Cell Res. 315(13):2141-53.
Thomas JA, Forbes SJ.  2009.  A fat chance for hepatocyte transplantation?Gut. 58(4):480-2.

2008

Hay DC, Fletcher J, Payne C, Terrace JD, Gallagher RCJ, Snoeys J, Black JR, Wojtacha D, Samuel K, Hannoun Z et al..  2008.  Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling.Proc Natl Acad Sci U S A. 105(34):12301-6.

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