Leading science, pioneering therapies

Liver stem cells and regeneration group publications

2016

Szkolnicka D, Lucendo-Villarin B, Moore JK, Simpson KJ, Forbes SJ, Hay DC.  2016.  Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs.Stem Cells Transl Med.
Oosthuyzen W, Scullion KM, Ivy JR, Morrison EE, Hunter RW, Lewis PJStarkey, O'Duibhir E, Street JM, Caporali A, Gregory CD et al..  2016.  Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells.J Am Soc Nephrol.

2015

Cameron K, Tan R, Schmidt-Heck W, Campos G, Lyall MJ, Wang Y, Lucendo-Villarin B, Szkolnicka D, Bates N, Kimber SJ et al..  2015.  Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes.Stem Cell Reports. 5(6):1250-62.
Hsieh W.-C., Mackinnon A.C, Lu W.-Y., Jung J., Boulter L., Henderson N.C, Simpson K.J, Schotanus B., Wojtacha D., Bird T.G et al..  2015.  Galectin-3 regulates hepatic progenitor cell expansion during liver injuryGut. 64(2):312-321.
Forbes SJ.  2015.  Organoid cultures boost human liver cell expansionHepatology. 62(5):1635-1637.
Muir KR, Lima MJoão, Docherty HM, Mcgowan NWA, Forbes S, Heremans Y, Forbes SJ, Heimberg H, Casey J, Docherty K.  2015.  Krüppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells following Expansion in Long Term Adherent Culture.PLoS One. 10(10):e0140352.
Moore JK, Mackinnon AC, Wojtacha D, Pope C, Fraser AR, Burgoyne P, Bailey L, Pass C, Atkinson A, Mcgowan NWA et al..  2015.  Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study.Cytotherapy.
Stutchfield BM, Antoine DJ, Mackinnon AC, Gow DJ, Bain CC, Hawley CA, Hughes M, Francis B, Wojtacha D, Man TY et al..  2015.  CSF1 Restores Innate Immunity Following Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure.Gastroenterology.
Villarin BLucendo, Cameron K, Szkolnicka D, Rashidi H., Bates N, Kimber SJ, Flint O, Forbes SJ, Iredale JP, Bradley M et al..  2015.  Polyurethane: Stable Cell Phenotype Requires Plasticity: Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance (Adv. Healthcare Mater. 12/2015).Adv Healthc Mater. 4(12):1819.
Lu W-Y, Bird TG, Boulter L, Tsuchiya A, Cole AM, Hay T, Guest RV, Wojtacha D, Man TYung, Mackinnon A et al..  2015.  Hepatic progenitor cells of biliary origin with liver repopulation capacity.Nat Cell Biol.
Lucendo-Villarin B, Cameron K, Szkolnicka D, Rashidi H., Bates N, Kimber SJ, Flint O, Forbes SJ, Iredale JP, Bradley M et al..  2015.  Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance.Adv Healthc Mater.
Forbes SJ, Gupta S, Dhawan A.  2015.  Cell therapy for liver disease: From liver transplantation to cell factory.J Hepatol. 62(1S):S157-S169.
Boulter L, Guest RV, Kendall TJ, Wilson DH, Wojtacha D, Robson AJ, Ridgway RA, Samuel K, van Rooijen N, Barry ST et al..  2015.  WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited.J Clin Invest.

2014

Yeung OWH, Lo C-M, Ling C-C, Qi X, Geng W, Li C-X, Ng KTP, Forbes SJ, Guan X-Y, Poon RTP et al..  2014.  Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma.J Hepatol.
Forbes SJ, Alison MR.  2014.  Regenerative medicine. Knocking on the door to successful hepatocyte transplantation.Nat Rev Gastroenterol Hepatol. 11(5):277-8.
Kallis YN, Scotton CJ, Mackinnon AC, Goldin RD, Wright NA, Iredale JP, Chambers RC, Forbes SJ.  2014.  Proteinase activated receptor 1 mediated fibrosis in a mouse model of liver injury: a role for bone marrow derived macrophages.PLoS One. 9(1):e86241.
Craig DG, Lee P, E Pryde A, Hidalgo E, Hayes PC, Wigmore SJ, Forbes SJ, Simpson KJ.  2014.  Markedly Increased High-Mobility Group Box 1 Protein in a Patient with Small-for-Size Syndrome.Case Rep Transplant. 2014:272498.
Sarvi S, Mackinnon AC, Avlonitis N, Bradley M, Rintoul RC, Rassl DM, Wang W, Forbes SJ, Gregory CD, Sethi T.  2014.  CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonist.Cancer Res. 74(5):1554-65.
Moore JK, Stutchfield BM, Forbes SJ.  2014.  Systematic review: the effects of autologous stem cell therapy for patients with liver disease.Aliment Pharmacol Ther. 39(7):673-85.

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