Leading science, pioneering therapies

Liver Tissue Development and Engineering group publications

2014

Hsieh W-C, Mackinnon AC, Lu W-Y, Jung J, Boulter L, Henderson NC, Simpson KJ, Schotanus B, Wojtacha D, Bird TG et al..  2014.  Galectin-3 regulates hepatic progenitor cell expansion during liver injury.Gut.

2013

Palakkan AA, Hay DC, Kumar PRAnil, Kumary TV, Ross JA.  2013.  Liver tissue engineering and cell sources: issues and challenges.Liver Int. 33(5):666-76.
Medine C.N, Lucendo-Villarin B, Storck C, Wang F, Szkolnicka D, Khan F, Pernagallo S, Black JR, Marriage HM, Ross JA et al..  2013.  Developing high-fidelity hepatotoxicity models from pluripotent stem cells.Stem Cells Transl Med. 2(7):505-9.
Szkolnicka D, Zhou W, Lucendo-Villarin B, Hay DC.  2013.  Pluripotent stem cell-derived hepatocytes: potential and challenges in pharmacology.Annu Rev Pharmacol Toxicol. 53:147-59.
Hay DC.  2013.  Rapid and scalable human stem cell differentiation: now in 3D.Stem Cells Dev. 22(20):2691-2.

2012

Zhou W, Hannoun Z, Jaffray E, Medine C.N, Black JR, Greenhough S, Zhu L, Ross JA, Forbes SJ, Wilmut I et al..  2012.  SUMOylation of HNF4α regulates protein stability and hepatocyte function.J Cell Sci. 125(Pt 15):3630-5.
Prendergast JGD, Tong P, Hay DC, Farrington SM, Semple CAM.  2012.  A genome-wide screen in human embryonic stem cells reveals novel sites of allele-specific histone modification associated with known disease loci.Epigenetics Chromatin. 5(1):6.
Pernagallo S, Tura O, Wu M, Samuel K, Diaz-Mochon JJose, Hansen A, Zhang R, Jackson M, Padfield GJ, Hadoke PWF et al..  2012.  Novel biopolymers to enhance endothelialisation of intra-vascular devices.Adv Healthc Mater. 1(5):646-56.

2011

Payne C, Samuel K, Pryde A, King J, Brownstein D, Schrader J, Medine C.N, Forbes SJ, Iredale JP, Newsome PN et al..  2011.  Persistence of functional hepatocyte-like cells in immune-compromised mice.Liver Int. 31(2):254-62.
Hay DC, Pernagallo S, Diaz-Mochon JJose, Medine C.N, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D et al..  2011.  Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.Stem Cell Res. 6(2):92-102.
Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G et al..  2011.  Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.Cell Res. 21(9):1332-42.

2010

Sharma R, Greenhough S, Medine C.N, Hay DC.  2010.  Three-dimensional culture of human embryonic stem cell derived hepatic endoderm and its role in bioartificial liver construction.J Biomed Biotechnol. 2010:236147.
Hay DC.  2010.  Cadaveric hepatocytes repopulate diseased livers: life after death.Gastroenterology. 139(3):729-31.
Terrace JD, Hay DC, Samuel K, Anderson RA, Currie IS, Parks RW, Forbes SJ, Ross JA.  2010.  Portal venous endothelium in developing human liver contains haematopoietic and epithelial progenitor cells.Exp Cell Res. 316(9):1637-47.
Greenhough S, Medine C.N, Hay DC.  2010.  Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening.Toxicology. 278(3):250-5.
Hannoun Z, Filippi C, Sullivan G, Hay DC, Iredale JP.  2010.  Hepatic endoderm differentiation from human embryonic stem cells.Curr Stem Cell Res Ther. 5(3):233-44.
Hannoun Z, Greenhough S, Jaffray E, Hay RT, Hay DC.  2010.  Post-translational modification by SUMO.Toxicology. 278(3):288-93.
Hay DC, Ross JA, Gallagher R, Bagnaninchi PO.  2010.  The complexities of engineering human stem cell-derived therapeutics.J Biomed Biotechnol. 2010:654964.
Sullivan G, Hay DC, Park I-H, Fletcher J, Hannoun Z, Payne C, Dalgetty D, Black JR, Ross JA, Samuel K et al..  2010.  Generation of functional human hepatic endoderm from human induced pluripotent stem cells.Hepatology. 51(1):329-35.

Pages