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The unconventional embryo: immune-restricted potential precedes multipotentiality.

TitleThe unconventional embryo: immune-restricted potential precedes multipotentiality.
Publication TypeJournal Article
Year of Publication2013
AuthorsMalouf C, Ottersbach K
JournalCell Stem Cell
Volume13
Issue5
Pagination509-10
Date Published2013 Nov 7
ISSN1875-9777
KeywordsAnimals, Female, Hematopoietic Stem Cells, Male
Abstract

Little is currently known about the developmental origins of the immune system and the lineage restriction processes that lead to its establishment. In this issue, Böiers et al. (2013) now demonstrate immune-restricted potential originating from the yolk sac even before the emergence of the first hematopoietic stem cells.

DOI10.1016/j.stem.2013.10.015
Alternate JournalCell Stem Cell
PubMed ID24209755
Grant List079249 / / Wellcome Trust / United Kingdom
100140 / / Wellcome Trust / United Kingdom
Publication institute
Other