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Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance.

TitlePolymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance.
Publication TypeJournal Article
Year of Publication2015
AuthorsLucendo-Villarin B, Cameron K, Szkolnicka D, Rashidi H., Bates N, Kimber SJ, Flint O, Forbes SJ, Iredale JP, Bradley M, Hay DC
JournalAdv Healthc Mater
Date Published2015 Jun 24
ISSN2192-2659
Abstract

In theory, pluripotent stem cells can give rise to all somatic cell types found in the human body. The ability to generate renewable sources of human cells has enormous potential to improve human health and wealth. One major obstacle to the routine deployment of stem cell-derived cells is their instability in culture. To tackle this issue a synthetic polymer surface is used.

DOI10.1002/adhm.201500391
Alternate JournalAdv Healthc Mater
PubMed ID26109270
Publication institute
CRM