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[Morphogenesis and growth potentials of organ cultures of the respiratory tract anlage of mice susceptible and resistant to pulmonary blastomogenesis].

Title[Morphogenesis and growth potentials of organ cultures of the respiratory tract anlage of mice susceptible and resistant to pulmonary blastomogenesis].
Publication TypeJournal Article
Year of Publication1986
AuthorsKolesnichenko TS, Medvinskiĭ AL
JournalOntogenez
Volume17
Issue3
Pagination293-302
Date Published1986 May-Jun
ISSN0475-1450
KeywordsAnimals, Disease Susceptibility, Lung, Lung Neoplasms, Mice, Mice, Inbred A, Mice, Inbred C57BL, Morphogenesis, Organ Culture Techniques, Phenotype, Respiratory System, Time Factors
Abstract

The morphogenesis and growth potencies have been studied in the long-term organ cultures of different parts of the respiratory tract early rudiment in the mouse strains susceptible (A) and resistant (C57BL) against lung blastomogenesis. Similarities and peculiarities have been shown for the lung rudiment cells developing in vitro and in vivo. The linear differences have been established in morphogenesis and growth potencies of the proximal and distal parts of the respiratory tract rudiment. Possible importance of phenotypic differences in realization of the genetically determined sensitivity of the mouse-lung tissue to spontaneous and induced blastomogenesis is discussed.

Alternate JournalOntogenez
PubMed ID3725294
Publication institute
Other