Leading science, pioneering therapies
CRM Publications

Derivation of the clinical grade human embryonic stem cell line RCe015-A (RC-11).

TitleDerivation of the clinical grade human embryonic stem cell line RCe015-A (RC-11).
Publication TypeJournal Article
Year of Publication2016
Authorsde Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Canham M, Kunath T, Downie JM, Bateman M, Courtney A
JournalStem Cell Res
Date Published2016 May 07

The human embryonic stem cell line RCe015-A (RC-11) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a fragmented cleavage stage embryo voluntarily donated as unsuitable or surplus to fertility requirements following informed consent. RCe015-A (RC-11) shows normal pluripotency marker expression and differentiation to the three germ layers in vitro and in vivo. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data are available.

Alternate JournalStem Cell Res
PubMed ID27558602
Publication institute