Publications
2015
Galectin-3 regulates hepatic progenitor cell expansion during liver injury
Hsieh, W.-C., Mackinnon A. C., Lu W.-Y., Jung J., Boulter L., Henderson N. C., Simpson K. J., Schotanus B., Wojtacha D., Bird T. G., et al.
, Gut, Jan-02-2015, Volume 64, Issue 2, p.312 - 321, (2015)
2014
Galectin-3 regulates hepatic progenitor cell expansion during liver injury.
Hsieh, Wei-Chen, Mackinnon Alison C., Lu Wei-Yu, Jung Jonathan, Boulter Luke, Henderson Neil C., Simpson Kenneth J., Schotanus Baukje, Wojtacha Davina, Bird Tom G., et al.
, Gut, 2014 May 16, (2014)
2013
Developing high-fidelity hepatotoxicity models from pluripotent stem cells.
Medine, C. N., Lucendo-Villarin Baltasar, Storck Christopher, Wang Faye, Szkolnicka Dagmara, Khan Ferdous, Pernagallo Salvatore, Black James R., Marriage Howard M., Ross James A., et al.
, Stem Cells Transl Med, 2013 Jul, Volume 2, Issue 7, p.505-9, (2013)
2012
SUMOylation of HNF4α regulates protein stability and hepatocyte function.
Zhou, Wenli, Hannoun Zara, Jaffray Ellis, Medine C. N., Black James R., Greenhough Sebastian, Zhu Liang, Ross James A., Forbes Stuart J., Wilmut Ian, et al.
, J Cell Sci, 2012 Aug 1, Volume 125, Issue Pt 15, p.3630-5, (2012)
2011
Persistence of functional hepatocyte-like cells in immune-compromised mice.
Payne, Catherine, Samuel Kay, Pryde Anne, King Jason, Brownstein David, Schrader Joerg, Medine C. N., Forbes Stuart J., Iredale John P., Newsome Philip N., et al.
, Liver Int, 2011 Feb, Volume 31, Issue 2, p.254-62, (2011)
Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.
Hay, David C., Pernagallo Salvatore, Diaz-Mochon Juan Jose, Medine C. N., Greenhough Sebastian, Hannoun Zara, Schrader Joerg, Black James R., Fletcher Judy, Dalgetty Donna, et al.
, Stem Cell Res, 2011 Mar, Volume 6, Issue 2, p.92-102, (2011)
2010
Role of stem-cell-derived hepatic endoderm in human drug discovery.
Medine, C. N., Greenhough Sebastian, and Hay David C.
, Biochem Soc Trans, 2010 Aug, Volume 38, Issue 4, p.1033-6, (2010)
Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening.
Greenhough, Sebastian, Medine C. N., and Hay David C.
, Toxicology, 2010 Dec 30, Volume 278, Issue 3, p.250-5, (2010)
The comparison between conditioned media and serum-free media in human embryonic stem cell culture and differentiation.
Hannoun, Zara, Fletcher Judy, Greenhough Sebastian, Medine C. N., Samuel Kay, Sharma Ruchi, Pryde Anne, Black James R., Ross James A., Wilmut Ian, et al.
, Cell Reprogram, 2010 Apr, Volume 12, Issue 2, p.133-40, (2010)
Three-dimensional culture of human embryonic stem cell derived hepatic endoderm and its role in bioartificial liver construction.
Sharma, Ruchi, Greenhough Sebastian, Medine C. N., and Hay David C.
, J Biomed Biotechnol, 2010, Volume 2010, p.236147, (2010)
2009
Progress and future challenges in stem cell-derived liver technologies.
Dalgetty, Donna, Medine C. N., Iredale John P., and Hay David C.
, Am J Physiol Gastrointest Liver Physiol, 2009 Aug, Volume 297, Issue 2, p.G241-8, (2009)