CRM Publications

Gupta K, Patani R, Baxter PS, Serio A, Story D, Tsujita T, Hayes JD, Pedersen RA, Hardingham GE, Chandran S.  2012.  Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.Cell Death Differ. 19(5):779-87.

Lynch MD, Smith AG, De Gobbi M, Flenley M, Hughes J, Vernimmen D, Ayyub H, Sharpe JA, Sloane-Stanley JA, Sutherland L et al..  2012.  An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.EMBO J. 31(2):317-29.

Patani R, Lewis PA, Trabzuni D, Puddifoot CA, Wyllie DJA, Walker R, Smith C, Hardingham GE, Weale M, Hardy J et al..  2012.  Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis.J Neurochem. 122(4):738-51.

Forrester LM, Jackson M.  2012.  Mechanism of action of HOXB4 on the hematopoietic differentiation of embryonic stem cells.Stem Cells. 30(3):379-85.

Navarro P, Festuccia N, Colby D, Gagliardi A, Mullin NP, Zhang W, Karwacki-Neisius V, Osorno R, Kelly D, Robertson M et al..  2012.  OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.EMBO J. 31(24):4547-62.

Corradetti B, Freile P, Pells S, Bagnaninchi PO, Park J, Fahmy TM, De Sousa PA.  2012.  Paracrine signalling events in embryonic stem cell renewal mediated by affinity targeted nanoparticles.Biomaterials. 33(28):6634-43.

Illingworth R, Botting CH, Grimes GR, Bickmore WA, Eskeland R.  2012.  PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.PLoS One. 7(4):e34848.

Zhuang L, Pound JD, Willems JJLP, A Taylor H, Forrester LM, Gregory CD.  2012.  Pure populations of murine macrophages from cultured embryonic stem cells. Application to studies of chemotaxis and apoptotic cell clearance.J Immunol Methods. 385(1-2):1-14.

Zhang L, Huang H, Zhou F, Schimmel J, Pardo CGontan, Zhang T, Barakat TStefan, Sheppard K-A, Mickanin C, Porter JA et al..  2012.  RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation.Mol Cell. 46(5):650-61.

Gontan C, Achame EMulugeta, Demmers J, Barakat TStefan, Rentmeester E, van IJcken W, J Grootegoed A, Gribnau J.  2012.  RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation.Nature. 485(7398):386-90.

Zhou W, Hannoun Z, Jaffray E, Medine C.N, Black JR, Greenhough S, Zhu L, Ross JA, Forbes SJ, Wilmut I et al..  2012.  SUMOylation of HNF4α regulates protein stability and hepatocyte function.J Cell Sci. 125(Pt 15):3630-5.

Hammachi F, Morrison GM, Sharov AA, Livigni A, Narayan S, Papapetrou EP, O'Malley J, Kaji K, Ko MSH, Ptashne M et al..  2012.  Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency.Cell Rep. 1(2):99-109.

Rostovskaya M, Fu J, Obst M, Baer I, Weidlich S, Wang H, Smith AG, Anastassiadis K, A Stewart F.  2012.  Transposon-mediated BAC transgenesis in human ES cells.Nucleic Acids Res. 40(19):e150.

Stacpoole SRL, Bilican B, Webber DJ, Luzhynskaya A, He XL, Compston A, Karadottir R, Franklin RJM, Chandran S.  2011.  Derivation of neural precursor cells from human ES cells at 3% O(2) is efficient, enhances survival and presents no barrier to regional specification and functional differentiation.Cell Death Differ. 18(6):1016-23.

Stacpoole SRL, Bilican B, Webber DJ, Luzhynskaya A, He XL, Compston A, Karadottir R, ffrench-Constant C, Chandran S.  2011.  Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen.Nat Protoc. 6(8):1229-40.

Arias AMartinez, Brickman JM.  2011.  Gene expression heterogeneities in embryonic stem cell populations: origin and function.Curr Opin Cell Biol. 23(6):650-6.

Wongtawan T, Taylor JE, Lawson KA, Wilmut I, Pennings S.  2011.  Histone H4K20me3 and HP1α are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells.J Cell Sci. 124(Pt 11):1878-90.

Krejciova Z, Pells S, Cancellotti E, Freile P, Bishop M, Samuel K, Barclay GR, Ironside JW, Manson JC, Turner ML et al..  2011.  Human embryonic stem cells rapidly take up and then clear exogenous human and animal prions in vitro.J Pathol. 223(5):635-45.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G et al..  2011.  Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.Cell Res. 21(9):1332-42.

Payne C, Samuel K, Pryde A, King J, Brownstein D, Schrader J, Medine C.N, Forbes SJ, Iredale JP, Newsome PN et al..  2011.  Persistence of functional hepatocyte-like cells in immune-compromised mice.Liver Int. 31(2):254-62.

Barakat TStefan, Rentmeester E, Sleutels F, J Grootegoed A, Gribnau J.  2011.  Precise BAC targeting of genetically polymorphic mouse ES cells.Nucleic Acids Res. 39(18):e121.

Festuccia N, Chambers I.  2011.  Quantification of pluripotency transcription factor levels in embryonic stem cells by flow cytometry.Curr Protoc Stem Cell Biol. Chapter 1:Unit1B.9.

Patani R, Hollins AJ, Wishart TM, Puddifoot CA, Alvarez S, de Lera AR, Wyllie DJA, Compston DAS, Pedersen RA, Gillingwater TH et al..  2011.  Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.Nat Commun. 2:214.

Barakat TStefan, Gunhanlar N, Pardo CGontan, Achame EMulugeta, Ghazvini M, Boers R, Kenter A, Rentmeester E, J Grootegoed A, Gribnau J.  2011.  RNF12 activates Xist and is essential for X chromosome inactivation.PLoS Genet. 7(1):e1002001.

Hay DC, Pernagallo S, Diaz-Mochon JJose, Medine C.N, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D et al..  2011.  Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.Stem Cell Res. 6(2):92-102.