CRM Publications

Mascarenhas MI, Parker A, Dzierzak E, Ottersbach K.  2009.  Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling.Blood. 114(21):4645-53.

Ledran MH, Krassowska A, Armstrong L, Dimmick I, Renström J, Lang R, Yung S, Santibanez-Coref M, Dzierzak E, Stojkovic M et al..  2008.  Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.Cell Stem Cell. 3(1):85-98.

Pimanda JE, Ottersbach K, Knezevic K, Kinston S, Chan WYI, Wilson NK, Landry J-R, Wood AD, Kolb-Kokocinski A, Green AR et al..  2007.  Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.Proc Natl Acad Sci U S A. 104(45):17692-7.

Terrace JD, Currie IS, Hay DC, Masson NM, Anderson RA, Forbes SJ, Parks RW, Ross JA.  2007.  Progenitor cell characterization and location in the developing human liver.Stem Cells Dev. 16(5):771-8.

O'Carroll D, Mecklenbrauker I, Das PPratim, Santana A, Koenig U, Enright AJ, Miska EA, Tarakhovsky A.  2007.  A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway.Genes Dev. 21(16):1999-2004.

Gribi R, Hook L, Ure J, Medvinsky AL.  2006.  The differentiation program of embryonic definitive hematopoietic stem cells is largely alpha4 integrin independent.Blood. 108(2):501-9.

Samokhvalov IM, Thomson AM, Lalancette C, Liakhovitskaia A, Ure J, Medvinsky AL.  2006.  Multifunctional reversible knockout/reporter system enabling fully functional reconstitution of the AML1/Runx1 locus and rescue of hematopoiesis.Genesis. 44(3):115-21.

Krassowska A, Gordon-Keylock S, Samuel K, Gilchrist D, Dzierzak E, Oostendorp R, Forrester LM, Ansell JD.  2006.  Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad-mesonephros microenvironment.Exp Cell Res. 312(18):3595-603.

Oostendorp RAJ, Medvinsky AL, Kusadasi N, Nakayama N, Harvey K, Orelio C, Ottersbach K, Covey T, Ploemacher RE, Saris C et al..  2002.  Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis.J Cell Sci. 115(Pt 10):2099-108.

Kortenjann M, Nehls M, Smith AG, Carsetti R, Schüler J, Köhler G, Boehm T.  2001.  Abnormal bone marrow stroma in mice deficient for nemo-like kinase, Nlk.Eur J Immunol. 31(12):3580-7.

Bucher K, Sofroniew MV, Pannell R, Impey H, Smith AG, Torres EM, Dunnett SB, Jin Y, Baer R, Rabbitts TH.  2000.  The T cell oncogene Tal2 is necessary for normal development of the mouse brain.Dev Biol. 227(2):533-44.

Medvinsky AL, Dzierzak E.  1999.  Development of the hematopoietic stem cell: can we describe it?Blood. 94(10):3613-4.

Medvinsky AL, Dzierzak E.  1998.  Development of the definitive hematopoietic hierarchy in the mouse.Dev Comp Immunol. 22(3):289-301.

Dzierzak E, Medvinsky AL, de Bruijn MFTR.  1998.  Qualitative and quantitative aspects of haematopoietic cell development in the mammalian embryo.Immunol Today. 19(5):228-36.

Medvinsky AL, Dzierzak E.  1996.  Definitive hematopoiesis is autonomously initiated by the AGM region.Cell. 86(6):897-906.

Hole N, Graham GJ, Menzel U, Ansell JD.  1996.  A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro.Blood. 88(4):1266-76.

Zmuidzinas A, Fischer KD, Lira SA, Forrester LM, Bryant S, Bernstein A, Barbacid M.  1995.  The vav proto-oncogene is required early in embryogenesis but not for hematopoietic development in vitro.EMBO J. 14(1):1-11.

Müller AM, Medvinsky AL, Strouboulis J, Grosveld F, Dzierzak E.  1994.  Development of hematopoietic stem cell activity in the mouse embryo.Immunity. 1(4):291-301.

Samuel K, Clarke AR, Ansell JD, Hooper ML.  1993.  Age-dependent selection against hypoxanthine phosphoribosyl transferase-deficient cells in mouse haematopoiesis.Development. 118(3):859-63.

Clarke AR, Maandag ER, van Roon M, van der Lugt NM, van der Valk M, Hooper ML, Berns A, H Riele te.  1992.  Requirement for a functional Rb-1 gene in murine development.Nature. 359(6393):328-30.

Ansell JD, Samuel K, Whittingham DG, Patek CE, Hardy K, Handyside AH, Jones KW, Muggleton-Harris AL, A Taylor H, Hooper ML.  1991.  Hypoxanthine phosphoribosyl transferase deficiency, haematopoiesis and fertility in the mouse.Development. 112(2):489-98.