CRM Publications

Jeziorska DM, Murray RJS, De Gobbi M, Gaentzsch R, Garrick D, Ayyub H, Chen T, Li E, Telenius J, Lynch M et al..  2017.  DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.Proc Natl Acad Sci U S A. 114(36):E7526-E7535.

Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth R, Webb S, Kerr ARW, Lyall MJ et al..  2016.  Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.Cancer Res. 76(10):3097-108.

Illingworth R, Gruenewald-Schneider U, De Sousa D, Webb S, Merusi C, Kerr ARW, James KD, Smith C, Walker R, Andrews R et al..  2015.  Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome.Nucleic Acids Res. 43(2):732-44.

Schultze FChristian, Andag R, Alwahsh SMohammad, Toncheva D, Maslyankov S, Yaramov N, von Ahsen N, Brandhorst G, Walson PD, Oellerich M et al..  2014.  FoxP3 demethylation is increased in human colorectal cancer and rat cholangiocarcinoma tissue.Clin Biochem. 47(3):201-5.

Carén H, Pollard SM, Beck S.  2013.  The good, the bad and the ugly: epigenetic mechanisms in glioblastoma.Mol Aspects Med. 34(4):849-62.

Di Giacomo M, Comazzetto S, Saini H, De Fazio S, Carrieri C, Morgan M, Vasiliauskaite L, Benes V, Enright AJ, O'Carroll D.  2013.  Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis.Mol Cell. 50(4):601-8.

Stricker SH, Feber A, Engström PG, Carén H, Kurian KM, Takashima Y, Watts C, Way M, Dirks P, Bertone P et al..  2013.  Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner.Genes Dev. 27(6):654-69.

Clouaire T, Webb S, Skene P, Illingworth R, Kerr A, Andrews R, Lee J-H, Skalnik D, Bird A.  2012.  Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.Genes Dev. 26(15):1714-28.

Lynch MD, Smith AG, De Gobbi M, Flenley M, Hughes J, Vernimmen D, Ayyub H, Sharpe JA, Sloane-Stanley JA, Sutherland L et al..  2012.  An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.EMBO J. 31(2):317-29.

Deaton AM, Webb S, Kerr ARW, Illingworth R, Guy J, Andrews R, Bird A.  2011.  Cell type-specific DNA methylation at intragenic CpG islands in the immune system.Genome Res. 21(7):1074-86.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G et al..  2011.  Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.Cell Res. 21(9):1332-42.

Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr ARW, Deaton A, Andrews R, James KD et al..  2010.  CpG islands influence chromatin structure via the CpG-binding protein Cfp1.Nature. 464(7291):1082-6.

Skene PJ, Illingworth R, Webb S, Kerr ARW, James KD, Turner DJ, Andrews R, Bird AP.  2010.  Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.Mol Cell. 37(4):457-68.

Illingworth R, Gruenewald-Schneider U, Webb S, Kerr ARW, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP.  2010.  Orphan CpG islands identify numerous conserved promoters in the mammalian genome.PLoS Genet. 6(9):e1001134.

Barakat TStefan, Jonkers I, Monkhorst K, Gribnau J.  2010.  X-changing information on X inactivation.Exp Cell Res. 316(5):679-87.

Illingworth R, Bird AP.  2009.  CpG islands--'a rough guide'.FEBS Lett. 583(11):1713-20.

Hayashi K, Lopes SMChuva de, Kaneda M, Tang F, Hajkova P, Lao K, O'Carroll D, Das PP, Tarakhovsky A, Miska EA et al..  2008.  MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.PLoS One. 3(3):e1738.

Illingworth R, Kerr A, Desousa D, Jørgensen H, Ellis P, Stalker J, Jackson D, Clee C, Plumb R, Rogers J et al..  2008.  A novel CpG island set identifies tissue-specific methylation at developmental gene loci.PLoS Biol. 6(1):e22.

Garrick D, Sharpe JA, Arkell R, Dobbie L, Smith AG, Wood WG, Higgs DR, Gibbons RJ.  2006.  Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues.PLoS Genet. 2(4):e58.

Blelloch R, Wang Z, Meissner A, Pollard SM, Smith A, Jaenisch R.  2006.  Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus.Stem Cells. 24(9):2007-13.

Jackson M, Krassowska A, Gilbert N, Chevassut T, Forrester LM, Ansell JD, Ramsahoye B.  2004.  Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.Mol Cell Biol. 24(20):8862-71.

Hendrich B, Tweedie S.  2003.  The methyl-CpG binding domain and the evolving role of DNA methylation in animals.Trends Genet. 19(5):269-77.

Prokhortchouk E, Hendrich B.  2002.  Methyl-CpG binding proteins and cancer: are MeCpGs more important than MBDs?Oncogene. 21(35):5394-9.

Hendrich B, Guy J, Ramsahoye B, Wilson V, Bird A.  2001.  Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.Genes Dev. 15(6):710-23.