CRM Publications

Jackson M, Ma R, A Taylor H, Axton RA, Easterbrook J, Kydonaki M, Olivier E, Marenah L, Stanley EG, Elefanty AG et al..  2016.  Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.Stem Cells Transl Med. 5(8):981-90.

Szkolnicka D, Farnworth SL, Lucendo-Villarin B, Storck C, Zhou W, Iredale JP, Flint O, Hay DC.  2014.  Accurate prediction of Drug Induced Liver Injury using stem cell-derived populations.Stem Cells Transl Med. 3(2):141-8.

Therizols P, Illingworth R, Courilleau C, Boyle S, Wood AJ, Bickmore WA.  2014.  Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells.Science. 346(6214):1238-42.

Barakat TStefan, Gribnau J.  2014.  Combined DNA-RNA fluorescent in situ hybridization (FISH) to study X chromosome inactivation in differentiated female mouse embryonic stem cells.J Vis Exp. (88)

Livesey MR, Bilican B, Qiu J, Rzechorzek NM, Haghi G, Burr K, Hardingham GE, Chandran S, Wyllie DJA.  2014.  Maturation of AMPAR composition and the GABAAR reversal potential in hPSC-derived cortical neurons.J Neurosci. 34(11):4070-5.

Williamson I, Berlivet S, Eskeland R, Boyle S, Illingworth R, Paquette D, Dostie J, Bickmore WA.  2014.  Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization.Genes Dev. 28(24):2778-91.

Barakat TStefan, Loos F, van Staveren S, Myronova E, Ghazvini M, J Grootegoed A, Gribnau J.  2014.  The trans-activator RNF12 and cis-acting elements effectuate X chromosome inactivation independent of X-pairing.Mol Cell. 53(6):965-78.

Torres-Padilla M-E, Chambers I.  2014.  Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage.Development. 141(11):2173-81.

Gagliardi A, Mullin NP, Tan ZYing, Colby D, Kousa AI, Halbritter F, Weiss JT, Felker A, Bezstarosti K, Favaro R et al..  2013.  A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.EMBO J. 32(16):2231-47.

Hamilton WB, Kaji K, Kunath T.  2013.  ERK2 suppresses self-renewal capacity of embryonic stem cells, but is not required for multi-lineage commitment.PLoS One. 8(4):e60907.

Huang C, Jackson M, Samuel K, A Taylor H, Lowell S, Forrester LM.  2013.  Haematopoietic differentiation is inhibited when Notch activity is enhanced in FLK1(+) mesoderm progenitors.Stem Cell Res. 11(3):1273-87.

Gupta K, Hardingham GE, Chandran S.  2013.  NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons.Neurosci Lett. 543:95-100.

Livigni A, Brickman JM.  2013.  Oct4: the final frontier, differentiation defining pluripotency.Dev Cell. 25(6):547-8.

Minkovsky A, Barakat TStefan, Sellami N, Chin MHenry, Gunhanlar N, Gribnau J, Plath K.  2013.  The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo.Cell Rep. 3(3):905-18.

de Wit E, Bouwman BAM, Zhu Y, Klous P, Splinter E, Verstegen MJAM, Krijger PHL, Festuccia N, Nora EP, Welling M et al..  2013.  The pluripotent genome in three dimensions is shaped around pluripotency factors.Nature. 501(7466):227-31.

Karwacki-Neisius V, Göke J, Osorno R, Halbritter F, Ng JHui, Weiße AY, Wong F, Gagliardi A, Mullin NP, Festuccia N et al..  2013.  Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.Cell Stem Cell. 12(5):531-45.

Festuccia N, Osorno R, Wilson V, Chambers I.  2013.  The role of pluripotency gene regulatory network components in mediating transitions between pluripotent cell states.Curr Opin Genet Dev. 23(5):504-11.

Fraser L, A Taylor H, Forrester LM.  2013.  SCF/KIT inhibition has a cumulative but reversible effect on the self-renewal of embryonic stem cells and on the survival of differentiating cells.Cell Reprogram. 15(4):259-68.

Davies OR, Lin C-Y, Radzisheuskaya A, Zhou X, Taube J, Blin G, Waterhouse A, Smith AG, Lowell S.  2013.  Tcf15 primes pluripotent cells for differentiation.Cell Rep. 3(2):472-84.

Morgani SM, Canham MA, Nichols J, Sharov AA, Migueles RPortero, Ko MSH, Brickman JM.  2013.  Totipotent embryonic stem cells arise in ground-state culture conditions.Cell Rep. 3(6):1945-57.

Meek S, Wei J, Sutherland L, Nilges B, Buehr M, Tomlinson SR, Thomson AJ, Burdon T.  2013.  Tuning of β-catenin activity is required to stabilize self-renewal of rat embryonic stem cells.Stem Cells. 31(10):2104-15.

Soufi A, Zaret KS.  2013.  Understanding impediments to cellular conversion to pluripotency by assessing the earliest events in ectopic transcription factor binding to the genome.Cell Cycle. 12(10):1487-91.

Clouaire T, Webb S, Skene P, Illingworth R, Kerr A, Andrews R, Lee J-H, Skalnik D, Bird A.  2012.  Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.Genes Dev. 26(15):1714-28.

Soufi A, Donahue G, Zaret KS.  2012.  Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome.Cell. 151(5):994-1004.

Jackson M, Axton RA, A Taylor H, Wilson JA, Gordon-Keylock S, Kokkaliaris KD, Brickman JM, Schulz H, Hummel O, Hübner N et al..  2012.  HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche.Stem Cells. 30(2):150-60.