Leading science, pioneering therapies

CRM Publications

Found 23 results
Filters: Keyword is Histones  [Clear All Filters]
2016
Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth R, Webb S, Kerr ARW, Lyall MJ et al..  2016.  Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.Cancer Res. 76(10):3097-108.
2015
Illingworth R, Moffat M, Mann AR, Read D, Hunter CJ, Pradeepa MM, Adams IR, Bickmore WA.  2015.  The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development.Genes Dev. 29(18):1897-902.
2013
Di Giacomo M, Comazzetto S, Saini H, De Fazio S, Carrieri C, Morgan M, Vasiliauskaite L, Benes V, Enright AJ, O'Carroll D.  2013.  Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis.Mol Cell. 50(4):601-8.
2012
Clouaire T, Webb S, Skene P, Illingworth R, Kerr A, Andrews R, Lee J-H, Skalnik D, Bird A.  2012.  Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.Genes Dev. 26(15):1714-28.
Illingworth R, Botting CH, Grimes GR, Bickmore WA, Eskeland R.  2012.  PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.PLoS One. 7(4):e34848.
2011
Wongtawan T, Taylor JE, Lawson KA, Wilmut I, Pennings S.  2011.  Histone H4K20me3 and HP1α are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells.J Cell Sci. 124(Pt 11):1878-90.
Takatsuka M, Osada-Oka M, Satoh EF, Kitadokoro K, Nishiuchi Y, Niki M, Inoue M, Iwai K, Arakawa T, Shimoji Y et al..  2011.  A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction.PLoS One. 6(6):e20985.
Mahapatra S, Dewari PS, Bhardwaj A, Bhargava P.  2011.  Yeast H2A.Z, FACT complex and RSC regulate transcription of tRNA gene through differential dynamics of flanking nucleosomes.Nucleic Acids Res. 39(10):4023-34.
2010
Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr ARW, Deaton A, Andrews R, James KD et al..  2010.  CpG islands influence chromatin structure via the CpG-binding protein Cfp1.Nature. 464(7291):1082-6.
Terrenoire E, McRonald F, Halsall JA, Page P, Illingworth R, A Taylor MR, Davison V, O'Neill LP, Turner BM.  2010.  Immunostaining of modified histones defines high-level features of the human metaphase epigenome.Genome Biol. 11(11):R110.
Skene PJ, Illingworth R, Webb S, Kerr ARW, James KD, Turner DJ, Andrews R, Bird AP.  2010.  Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.Mol Cell. 37(4):457-68.
Illingworth R, Gruenewald-Schneider U, Webb S, Kerr ARW, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP.  2010.  Orphan CpG islands identify numerous conserved promoters in the mammalian genome.PLoS Genet. 6(9):e1001134.
2008
Bru T, Clarke C, McGrew MJ, Sang HM, Wilmut I, J Blow J.  2008.  Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts.Exp Cell Res. 314(14):2634-42.
2007
Rybtsova N, Leimgruber E, Seguín-Estévez Q, Dunand-Sauthier I, Krawczyk M, Reith W.  2007.  Transcription-coupled deposition of histone modifications during MHC class II gene activation.Nucleic Acids Res. 35(10):3431-41.
2005
Kunath T, Arnaud D, Uy GD, Okamoto I, Chureau C, Yamanaka Y, Heard E, Gardner RL, Avner P, Rossant J.  2005.  Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts.Development. 132(7):1649-61.
2004
Krawczyk M, Peyraud N, Rybtsova N, Masternak K, Bucher P, le Barras E, Reith W.  2004.  Long distance control of MHC class II expression by multiple distal enhancers regulated by regulatory factor X complex and CIITA.J Immunol. 173(10):6200-10.
Jackson M, Krassowska A, Gilbert N, Chevassut T, Forrester LM, Ansell JD, Ramsahoye B.  2004.  Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.Mol Cell Biol. 24(20):8862-71.
2002
Lagger G, O'Carroll D, Rembold M, Khier H, Tischler J, Weitzer G, Schuettengruber B, Hauser C, Brunmeir R, Jenuwein T et al..  2002.  Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.EMBO J. 21(11):2672-81.
Peters AHFM, Mermoud JE, O'Carroll D, Pagani M, Schweizer D, Brockdorff N, Jenuwein T.  2002.  Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.Nat Genet. 30(1):77-80.
2001
Hendrich B, Bickmore WA.  2001.  Human diseases with underlying defects in chromatin structure and modification.Hum Mol Genet. 10(20):2233-42.
Peters AH, O'Carroll D, Scherthan H, Mechtler K, Sauer S, Schöfer C, Weipoltshammer K, Pagani M, Lachner M, Kohlmaier A et al..  2001.  Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.Cell. 107(3):323-37.
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T.  2001.  Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.Nature. 410(6824):116-20.
Nielsen SJ, Schneider R, Bauer UM, Bannister AJ, Morrison A, O'Carroll D, Firestein R, Cleary M, Jenuwein T, Herrera RE et al..  2001.  Rb targets histone H3 methylation and HP1 to promoters.Nature. 412(6846):561-5.