Leading science, pioneering therapies

CRM Publications

Found 30 results
Filters: Keyword is Myelin Sheath  [Clear All Filters]
Bechler ME, ffrench-Constant C.  2014.  Neuroscience. A new wrap for neuronal activity?Science. 344(6183):480-1.
Stoffels JMJ, de Jonge JC, Stancic M, Nomden A, van Strien ME, Ma D, Sisková Z, Maier O, ffrench-Constant C, Franklin RJM et al..  2013.  Fibronectin aggregation in multiple sclerosis lesions impairs remyelination.Brain. 136(Pt 1):116-31.
Czopka T, ffrench-Constant C, Lyons DA.  2013.  Individual oligodendrocytes have only a few hours in which to generate new myelin sheaths in vivo.Dev Cell. 25(6):599-609.
Barateiro A, Miron VE, Santos SD, Relvas JB, Fernandes A, ffrench-Constant C, Brites D.  2013.  Unconjugated bilirubin restricts oligodendrocyte differentiation and axonal myelination.Mol Neurobiol. 47(2):632-44.
Münzel EJolanda, Schaefer K, Obirei B, Kremmer E, Burton EA, Kuscha V, Becker CG, Brösamle C, Williams AC, Becker T.  2012.  Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish.Glia. 60(2):253-70.
Hampton DW, Innes N, Merkler D, Zhao C, Franklin RJM, Chandran S.  2012.  Focal immune-mediated white matter demyelination reveals an age-associated increase in axonal vulnerability and decreased remyelination efficiency.Am J Pathol. 180(5):1897-905.
Jarjour AA, Zhang H, Bauer N, ffrench-Constant C, Williams AC.  2012.  In vitro modeling of central nervous system myelination and remyelination.Glia. 60(1):1-12.
Wu LMan N, Williams AC, Delaney A, Sherman DL, Brophy PJ.  2012.  Increasing internodal distance in myelinated nerves accelerates nerve conduction to a flat maximum.Curr Biol. 22(20):1957-61.
Zhang H, Jarjour AA, Boyd A, Williams AC.  2011.  Central nervous system remyelination in culture--a tool for multiple sclerosis research.Exp Neurol. 230(1):138-48.
le Piaton G, Aigrot M-S, Williams AC, Moyon S, Tepavcevic V, Moutkine I, Gras J, Matho KS, Schmitt A, Soellner H et al..  2011.  Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system.Brain. 134(Pt 4):1156-67.
Almeida RG, Czopka T, ffrench-Constant C, Lyons DA.  2011.  Individual axons regulate the myelinating potential of single oligodendrocytes in vivo.Development. 138(20):4443-50.
Huang JK, Fancy SPJ, Zhao C, Rowitch DH, ffrench-Constant C, Franklin RJM.  2011.  Myelin regeneration in multiple sclerosis: targeting endogenous stem cells.Neurotherapeutics. 8(4):650-8.
Huang JK, Jarjour AA, Oumesmar BNait, Kerninon C, Williams AC, Krezel W, Kagechika H, Bauer J, Zhao C, Van Evercooren ABaron- et al..  2011.  Retinoid X receptor gamma signaling accelerates CNS remyelination.Nat Neurosci. 14(1):45-53.
Laursen LS, Chan CW, ffrench-Constant C.  2011.  Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K.J Cell Biol. 192(5):797-811.
Laursen LS, Chan CW, ffrench-Constant C.  2009.  An integrin-contactin complex regulates CNS myelination by differential Fyn phosphorylation.J Neurosci. 29(29):9174-85.
Câmara J, Wang Z, Nunes-Fonseca C, Friedman HC, Grove M, Sherman DL, Komiyama NH, Grant SG, Brophy PJ, Peterson A et al..  2009.  Integrin-mediated axoglial interactions initiate myelination in the central nervous system.J Cell Biol. 185(4):699-712.
Baer AS, Syed YA, Kang SUng, Mitteregger D, Vig R, ffrench-Constant C, Franklin RJM, Altmann F, Lubec G, Kotter MR.  2009.  Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling.Brain. 132(Pt 2):465-81.
Bauer NG, ffrench-Constant C.  2009.  Physical forces in myelination and repair: a question of balance?J Biol. 8(8):78.
Bauer NG, Richter-Landsberg C, ffrench-Constant C.  2009.  Role of the oligodendroglial cytoskeleton in differentiation and myelination.Glia. 57(16):1691-705.
Czopka T, Von Holst A, Schmidt G, ffrench-Constant C, Faissner A.  2009.  Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway.Glia. 57(16):1790-801.
Hampton DW, Anderson J, Pryce G, Irvine K-A, Giovannoni G, Fawcett JW, Compston A, Franklin RJM, Baker D, Chandran S.  2008.  An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss.J Neuroimmunol. 201-202:200-11.
Zhao C, Fancy SPJ, ffrench-Constant C, Franklin RJM.  2008.  Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination.Neurobiol Dis. 31(2):209-17.
Franklin RJM, ffrench-Constant C.  2008.  Remyelination in the CNS: from biology to therapy.Nat Rev Neurosci. 9(11):839-55.
Glaser T, Pollard SM, Smith A, Brüstle O.  2007.  Tripotential differentiation of adherently expandable neural stem (NS) cells.PLoS One. 2(3):e298.
Chandran S, Compston A.  2005.  Neural stem cells as a potential source of oligodendrocytes for myelin repair.J Neurol Sci. 233(1-2):179-81.