CRM Publications

van Erp S, van den Heuvel DMA, Fujita Y, Robinson RA, Hellemons AJCGM, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JAA et al..  2015.  Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.Dev Cell. 35(5):537-52.

Lavasani M, Thompson SD, Pollett JB, Usas A, Lu A, Stolz DB, Clark KA, Sun B, Péault B, Huard J.  2014.  Human muscle-derived stem/progenitor cells promote functional murine peripheral nerve regeneration.J Clin Invest. 124(4):1745-56.

Livesey MR, Bilican B, Qiu J, Rzechorzek NM, Haghi G, Burr K, Hardingham GE, Chandran S, Wyllie DJA.  2014.  Maturation of AMPAR composition and the GABAAR reversal potential in hPSC-derived cortical neurons.J Neurosci. 34(11):4070-5.

Bechler ME, ffrench-Constant C.  2014.  Neuroscience. A new wrap for neuronal activity?Science. 344(6183):480-1.

Bilican B, Livesey MR, Haghi G, Qiu J, Burr K, Siller R, Hardingham GE, Wyllie DJA, Chandran S.  2014.  Physiological normoxia and absence of EGF is required for the long-term propagation of anterior neural precursors from human pluripotent cells.PLoS One. 9(1):e85932.

Jaarsma D, van den Berg R, Wulf PS, van Erp S, Keijzer N, Schlager MA, de Graaff E, De Zeeuw CI, R Pasterkamp J, Akhmanova A et al..  2014.  A role for Bicaudal-D2 in radial cerebellar granule cell migration.Nat Commun. 5:3411.

van Gestel MA, van Erp S, Sanders LE, Brans MAD, Luijendijk MCM, Merkestein M, Pasterkamp RJ, Adan RAH.  2014.  shRNA-induced saturation of the microRNA pathway in the rat brain.Gene Ther. 21(2):205-11.

Tan CLek, Plotkin JL, Venø MT, von Schimmelmann M, Feinberg P, Mann S, Handler A, Kjems J, D Surmeier J, O'Carroll D et al..  2013.  MicroRNA-128 governs neuronal excitability and motor behavior in mice.Science. 342(6163):1254-8.

Gupta K, Hardingham GE, Chandran S.  2013.  NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons.Neurosci Lett. 543:95-100.

Eva R, Crisp S, Marland JRK, Norman JC, Kanamarlapudi V, ffrench-Constant C, Fawcett JW.  2012.  ARF6 directs axon transport and traffic of integrins and regulates axon growth in adult DRG neurons.J Neurosci. 32(30):10352-64.

Falk A, Koch P, Kesavan J, Takashima Y, Ladewig J, Alexander M, Wiskow O, Tailor J, Trotter M, Pollard SM et al..  2012.  Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons.PLoS One. 7(1):e29597.

Kan AA, van Erp S, Derijck AAHA, de Wit M, Hessel EVS, O'Duibhir E, de Jager W, Van Rijen PC, Gosselaar PH, de Graan PNE et al..  2012.  Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response.Cell Mol Life Sci. 69(18):3127-45.

Tan CLik, Kwok JCF, Patani R, ffrench-Constant C, Chandran S, Fawcett JW.  2011.  Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling.J Neurosci. 31(17):6289-95.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G et al..  2011.  Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.Cell Res. 21(9):1332-42.

Bell KF, Al-Mubarak B, Fowler JH, Baxter PS, Gupta K, Tsujita T, Chowdhry S, Patani R, Chandran S, Horsburgh K et al..  2011.  Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.Proc Natl Acad Sci U S A. 108(1):E1-2;authorreplyE3-4.

Hook L, Vives J, Fulton N, Leveridge M, Lingard S, Bootman MD, Falk A, Pollard SM, Allsopp TE, Dalma-Weiszhausz D et al..  2011.  Non-immortalized human neural stem (NS) cells as a scalable platform for cellular assays.Neurochem Int. 59(3):432-44.

Devine MJ, Ryten M, Vodicka P, Thomson AJ, Burdon T, Houlden H, Cavaleri F, Nagano M, Drummond N, Taanman J-W et al..  2011.  Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus.Nat Commun. 2:440.

Anderson JMarian, Patani R, Reynolds R, Nicholas R, Compston A, Spillantini MGrazia, Chandran S.  2010.  Abnormal tau phosphorylation in primary progressive multiple sclerosis.Acta Neuropathol. 119(5):591-600.

Schaefer A, Im H-I, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny PJ, O'Carroll D, Greengard P.  2010.  Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction.J Exp Med. 207(9):1843-51.

Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MGrazia, Chandran S.  2010.  Cell-mediated neuroprotection in a mouse model of human tauopathy.J Neurosci. 30(30):9973-83.

Hardingham GE, Patani R, Baxter PS, Wyllie DJ, Chandran S.  2010.  Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration.Mol Neurobiol. 42(1):97-102.

Iovino M, Patani R, Watts C, Chandran S, Spillantini MGrazia.  2010.  Human stem cell-derived neurons: a system to study human tau function and dysfunction.PLoS One. 5(11):e13947.

Danovi D, Falk A, Humphreys P, Vickers R, Tinsley J, Smith AG, Pollard SM.  2010.  Imaging-based chemical screens using normal and glioma-derived neural stem cells.Biochem Soc Trans. 38(4):1067-71.

Skene PJ, Illingworth R, Webb S, Kerr ARW, James KD, Turner DJ, Andrews R, Bird AP.  2010.  Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.Mol Cell. 37(4):457-68.

Eva R, Dassie E, Caswell PT, Dick G, ffrench-Constant C, Norman JC, Fawcett JW.  2010.  Rab11 and its effector Rab coupling protein contribute to the trafficking of beta 1 integrins during axon growth in adult dorsal root ganglion neurons and PC12 cells.J Neurosci. 30(35):11654-69.