CRM Publications

Soufi A, Garcia MFernandez, Jaroszewicz A, Osman N, Pellegrini M, Zaret KS.  2015.  Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming.Cell. 161(3):555-68.

Alami NH, Smith RB, Carrasco MA, Williams LA, Winborn CS, Han SSW, Kiskinis E, Winborn B, Freibaum BD, Kanagaraj A et al..  2014.  Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.Neuron. 81(3):536-43.

Livigni A, Brickman JM.  2013.  Oct4: the final frontier, differentiation defining pluripotency.Dev Cell. 25(6):547-8.

de Wit E, Bouwman BAM, Zhu Y, Klous P, Splinter E, Verstegen MJAM, Krijger PHL, Festuccia N, Nora EP, Welling M et al..  2013.  The pluripotent genome in three dimensions is shaped around pluripotency factors.Nature. 501(7466):227-31.

Karwacki-Neisius V, Göke J, Osorno R, Halbritter F, Ng JHui, Weiße AY, Wong F, Gagliardi A, Mullin NP, Festuccia N et al..  2013.  Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.Cell Stem Cell. 12(5):531-45.

Soufi A, Zaret KS.  2013.  Understanding impediments to cellular conversion to pluripotency by assessing the earliest events in ectopic transcription factor binding to the genome.Cell Cycle. 12(10):1487-91.

Osorno R, Tsakiridis A, Wong F, Cambray N, Economou C, Wilkie R, Blin G, Scotting PJ, Chambers I, Wilson V.  2012.  The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression.Development. 139(13):2288-98.

Soufi A, Donahue G, Zaret KS.  2012.  Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome.Cell. 151(5):994-1004.

Hammachi F, Morrison GM, Sharov AA, Livigni A, Narayan S, Papapetrou EP, O'Malley J, Kaji K, Ko MSH, Ptashne M et al..  2012.  Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency.Cell Rep. 1(2):99-109.

Rostovskaya M, Fu J, Obst M, Baer I, Weidlich S, Wang H, Smith AG, Anastassiadis K, A Stewart F.  2012.  Transposon-mediated BAC transgenesis in human ES cells.Nucleic Acids Res. 40(19):e150.

Festuccia N, Chambers I.  2011.  Quantification of pluripotency transcription factor levels in embryonic stem cells by flow cytometry.Curr Protoc Stem Cell Biol. Chapter 1:Unit1B.9.

Osorno R, Chambers I.  2011.  Transcription factor heterogeneity and epiblast pluripotency.Philos Trans R Soc Lond B Biol Sci. 366(1575):2230-7.

Navarro P, Moffat M, Mullin NP, Chambers I.  2011.  The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.Hum Genet. 130(2):255-64.

Lagger S, Meunier D, Mikula M, Brunmeir R, Schlederer M, Artaker M, Pusch O, Egger G, Hagelkruys A, Mikulits W et al..  2010.  Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans.EMBO J. 29(23):3992-4007.

Canham MA, Sharov AA, Ko MSH, Brickman JM.  2010.  Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript.PLoS Biol. 8(5):e1000379.

Navarro P, Oldfield A, Legoupi J, Festuccia N, Dubois A, Attia M, Schoorlemmer J, Rougeulle C, Chambers I, Avner P.  2010.  Molecular coupling of Tsix regulation and pluripotency.Nature. 468(7322):457-60.

van den Berg DLC, Snoek T, Mullin NP, Yates A, Bezstarosti K, Demmers J, Chambers I, Poot RA.  2010.  An Oct4-centered protein interaction network in embryonic stem cells.Cell Stem Cell. 6(4):369-81.

Hall J, Guo G, Wray J, Eyres I, Nichols J, Grotewold L, Morfopoulou S, Humphreys P, Mansfield W, Walker R et al..  2009.  Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.Cell Stem Cell. 5(6):597-609.

Vallier L, Touboul T, Brown S, Cho C, Bilican B, Alexander M, Cedervall J, Chandran S, Ahrlund-Richter L, Weber A et al..  2009.  Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells.Stem Cells. 27(11):2655-66.

Chambers I, Tomlinson SR.  2009.  The transcriptional foundation of pluripotency.Development. 136(14):2311-22.

van den Berg DLC, Zhang W, Yates A, Engelen E, Takacs K, Bezstarosti K, Demmers J, Chambers I, Poot RA.  2008.  Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression.Mol Cell Biol. 28(19):5986-95.

Navarro P, Chambers I, Karwacki-Neisius V, Chureau C, Morey C, Rougeulle C, Avner P.  2008.  Molecular coupling of Xist regulation and pluripotency.Science. 321(5896):1693-5.

Bru T, Clarke C, McGrew MJ, Sang HM, Wilmut I, J Blow J.  2008.  Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts.Exp Cell Res. 314(14):2634-42.

Morrison GM, Brickman JM.  2006.  Conserved roles for Oct4 homologues in maintaining multipotency during early vertebrate development.Development. 133(10):2011-22.

Silva J, Chambers I, Pollard SM, Smith A.  2006.  Nanog promotes transfer of pluripotency after cell fusion.Nature. 441(7096):997-1001.