CRM Publications

Vaidya HJayesh, Leon ABriones, C Blackburn C.  2016.  FOXN1 in thymus organogenesis and development.Eur J Immunol. 46(8):1826-37.

Luis TC, Luc S, Mizukami T, Boukarabila H, Thongjuea S, Woll PS, Azzoni E, Giustacchini A, Lutteropp M, Bouriez-Jones T et al..  2016.  Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.Nat Immunol. 17(12):1424-1435.

Sheridan JM, C Blackburn C.  2014.  Generation of tissue organoids by compaction reaggregation.Methods Mol Biol. 1092:143-51.

Bredenkamp N, Nowell CS, C Blackburn C.  2014.  Regeneration of the aged thymus by a single transcription factor.Development. 141(8):1627-37.

Farley A, Morris LX, Vroegindeweij E, Depreter MGL, Vaidya HJayesh, Stenhouse FH, Tomlinson SR, Anderson RA, Cupedo T, Cornelissen JJ et al..  2013.  Dynamics of thymus organogenesis and colonization in early human development.Development. 140(9):2015-26.

Garfin PM, Min D, Bryson JL, Serwold T, Edris B, C Blackburn C, Richie ER, Weinberg KI, Manley NR, Sage J et al..  2013.  Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression.J Exp Med. 210(6):1087-97.

Luc S, Luis TC, Boukarabila H, Macaulay IC, Buza-Vidas N, Bouriez-Jones T, Lutteropp M, Woll PS, Loughran SJ, Mead AJ et al..  2012.  The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.Nat Immunol. 13(4):412-9.

Nowell CS, Bredenkamp N, Tetélin S, Jin X, Tischner C, Vaidya HJayesh, Sheridan JM, Stenhouse FH, Heussen R, Smith AG et al..  2011.  Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence.PLoS Genet. 7(11):e1002348.

Manley NR, Richie E, C Blackburn C, Condie BGene, Sage J.  2011.  Structure and function of the thymic microenvironment.Front Biosci (Landmark Ed). 16:2461-77.

Foster KE, Gordon J, Cardenas K, Veiga-Fernandes H, Makinen T, Grigorieva EF, Wilkinson DG, C Blackburn C, Richie E, Manley NR et al..  2010.  EphB-ephrin-B2 interactions are required for thymus migration during organogenesis.Proc Natl Acad Sci U S A. 107(30):13414-9.

Bonfanti P, Claudinot S, Amici AW, Farley A, C Blackburn C, Barrandon Y.  2010.  Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells.Nature. 466(7309):978-82.

Liu Z, Farley A, Chen L, Kirby BJ, Kovacs CS, C Blackburn C, Manley NR.  2010.  Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions.PLoS Genet. 6(12):e1001251.

Sheridan JM, Taoudi S, Medvinsky AL, C Blackburn C.  2009.  A novel method for the generation of reaggregated organotypic cultures that permits juxtaposition of defined cell populations.Genesis. 47(5):346-51.

Foster K, Sheridan JM, Veiga-Fernandes H, Roderick K, Pachnis V, Adams R, C Blackburn C, Kioussis D, Coles M.  2008.  Contribution of neural crest-derived cells in the embryonic and adult thymus.J Immunol. 180(5):3183-9.

Depreter MGL, Blair NF, Gaskell TL, Nowell CS, Davern K, Pagliocca A, Stenhouse FH, Farley A, Fraser A, Vrana J et al..  2008.  Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells.Proc Natl Acad Sci U S A. 105(3):961-6.

DeMonte L, Porcellini S, Tafi E, Sheridan JM, Gordon J, Depreter MGL, Blair NF, Panigada M, Sanvito F, Merati B et al..  2007.  EVA regulates thymic stromal organisation and early thymocyte development.Biochem Biophys Res Commun. 356(2):334-40.

Nowell CS, Farley A, C Blackburn C.  2007.  Thymus organogenesis and development of the thymic stroma.Methods Mol Biol. 380:125-62.

Patel SR, Gordon J, Mahbub F, C Blackburn C, Manley NR.  2006.  Bmp4 and Noggin expression during early thymus and parathyroid organogenesis.Gene Expr Patterns. 6(8):794-9.

Morris L, Gordon J, C Blackburn C.  2006.  Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.Mamm Genome. 17(2):178-87.

Gordon J, Wilson V, Moore-Scott BA, Manley NR, C Blackburn C.  2005.  In vivo and in vitro assays of thymic organogenesis.Methods Mol Med. 105:303-10.

C Blackburn C, Manley NR.  2004.  Developing a new paradigm for thymus organogenesis.Nat Rev Immunol. 4(4):278-89.

Gordon J, Wilson V, Blair NF, Sheridan JM, Farley A, Wilson L, Manley NR, C Blackburn C.  2004.  Functional evidence for a single endodermal origin for the thymic epithelium.Nat Immunol. 5(5):546-53.

Manley NR, C Blackburn C.  2003.  A developmental look at thymus organogenesis: where do the non-hematopoietic cells in the thymus come from?Curr Opin Immunol. 15(2):225-32.

Jackson M, Baird JW, Nichols J, Wilkie R, Ansell JD, Graham GJ, Forrester LM.  2003.  Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.Dev Dyn. 228(4):740-4.

Gordon J, Bennett AR, C Blackburn C, Manley NR.  2001.  Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch.Mech Dev. 103(1-2):141-3.