Leading science, pioneering therapies

CRM Publications

Found 12 results
Filters: Keyword is Mutagenesis, Site-Directed  [Clear All Filters]
2010
Yang J-S, Maurin T, Robine N, Rasmussen KD, Jeffrey KL, Chandwani R, Papapetrou EP, Sadelain M, O'Carroll D, Lai EC.  2010.  Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis.Proc Natl Acad Sci U S A. 107(34):15163-8.
2003
Testa G, Zhang Y, Vintersten K, Benes V, Pijnappel WWMPim, Chambers I, Smith AG, Smith AG, A Stewart F.  2003.  Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.Nat Biotechnol. 21(4):443-7.
2002
Roberts C, Sutherland HF, Farmer H, Kimber W, Halford S, Carey A, Brickman JM, Wynshaw-Boris A, Scambler PJ.  2002.  Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality.Mol Cell Biol. 22(7):2318-28.
1998
Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I, Schöler H, Smith A.  1998.  Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4.Cell. 95(3):379-91.
Niwa H, Burdon T, Chambers I, Smith A.  1998.  Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3.Genes Dev. 12(13):2048-60.
1997
Jost B, Duluc I, Richardson M, Lathe R, Freund JN.  1997.  Functional diversity and interactions between the repeat domains of rat intestinal lactase.Biochem J. 327 ( Pt 1):95-103.
Townley DJ, Avery BJ, Rosen B, Skarnes WC.  1997.  Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice.Genome Res. 7(3):293-8.
1996
Ellison AR, Bishop JO.  1996.  Initiation of herpes simplex virus thymidine kinase polypeptides.Nucleic Acids Res. 24(11):2073-9.
1995
Ellison AR, Wallace H, al-Shawi R, Bishop JO.  1995.  Different transmission rates of herpesvirus thymidine kinase reporter transgenes from founder male parents and male parents of subsequent generations.Mol Reprod Dev. 41(4):425-34.
Dear TN, Colledge WH, Carlton MB, Lavenir I, Larson T, Smith AG, Warren AJ, Evans MJ, Sofroniew MV, Rabbitts TH.  1995.  The Hox11 gene is essential for cell survival during spleen development.Development. 121(9):2909-15.
Johnson D, Harrison S, Pineda N, Heinlein C, al-Shawi R, Bishop JO.  1995.  Localization of the response elements of a gene induced by intermittent growth hormone stimulation.J Mol Endocrinol. 14(1):35-49.
1994
Macleod D, Charlton J, Mullins JJ, Bird AP.  1994.  Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island.Genes Dev. 8(19):2282-92.