CRM Publications

Lopez-Yrigoyen M, Yang C-T, Fidanza A, Cassetta L, A Taylor H, McCahill A, Sellink E, Von Lindern M, van den Akker E, Mountford JC et al..  2019.  Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.Nat Commun. 10(1):881.

Böiers C, Richardson SE, Laycock E, Zriwil A, Turati VA, Brown J, Wray JP, Wang D, James C, Herrero J et al..  2018.  A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.Dev Cell. 44(3):362-377.e7.

Xu M, Stattin E-L, Shaw G, Heinegård D, Sullivan G, Wilmut I, Colman A, nnerfjord PÖ, Khabut A, Aspberg A et al..  2016.  Chondrocytes Derived From Mesenchymal Stromal Cells and Induced Pluripotent Cells of Patients With Familial Osteochondritis Dissecans Exhibit an Endoplasmic Reticulum Stress Response and Defective Matrix Assembly.Stem Cells Transl Med. 5(9):1171-81.

Soufi A, Garcia MFernandez, Jaroszewicz A, Osman N, Pellegrini M, Zaret KS.  2015.  Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming.Cell. 161(3):555-68.

Serio A, Bilican B, Barmada SJ, Ando DMichael, Zhao C, Siller R, Burr K, Haghi G, Story D, Nishimura AL et al..  2013.  Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.Proc Natl Acad Sci U S A. 110(12):4697-702.

O'Malley J, Skylaki S, Iwabuchi KA, Chantzoura E, Ruetz T, Johnsson A, Tomlinson SR, Linnarsson S, Kaji K.  2013.  High-resolution analysis with novel cell-surface markers identifies routes to iPS cells.Nature. 499(7456):88-91.

de Wit E, Bouwman BAM, Zhu Y, Klous P, Splinter E, Verstegen MJAM, Krijger PHL, Festuccia N, Nora EP, Welling M et al..  2013.  The pluripotent genome in three dimensions is shaped around pluripotency factors.Nature. 501(7466):227-31.

Soufi A, Zaret KS.  2013.  Understanding impediments to cellular conversion to pluripotency by assessing the earliest events in ectopic transcription factor binding to the genome.Cell Cycle. 12(10):1487-91.

Bilican B, Serio A, Shaw CE, Maniatis T, Chandran S.  2013.  Unpicking neurodegeneration in a dish with human pluripotent stem cells: one cell type at a time.Cell Cycle. 12(15):2339-40.

Borooah S, Phillips MJ, Bilican B, Wright AF, Wilmut I, Chandran S, Gamm D, Dhillon B.  2013.  Using human induced pluripotent stem cells to treat retinal disease.Prog Retin Eye Res. 37:163-81.

Falk A, Koch P, Kesavan J, Takashima Y, Ladewig J, Alexander M, Wiskow O, Tailor J, Trotter M, Pollard SM et al..  2012.  Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons.PLoS One. 7(1):e29597.

Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan G, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J et al..  2012.  Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.Proc Natl Acad Sci U S A. 109(15):5803-8.

Skylaki S, Tomlinson SR.  2012.  Recurrent transcriptional clusters in the genome of mouse pluripotent stem cells.Nucleic Acids Res. 40(19):e153.

Hammachi F, Morrison GM, Sharov AA, Livigni A, Narayan S, Papapetrou EP, O'Malley J, Kaji K, Ko MSH, Ptashne M et al..  2012.  Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency.Cell Rep. 1(2):99-109.

Thomson SR, Wishart TM, Patani R, Chandran S, Gillingwater TH.  2012.  Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality?J Anat. 220(2):122-30.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G et al..  2011.  Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.Cell Res. 21(9):1332-42.

Devine MJ, Ryten M, Vodicka P, Thomson AJ, Burdon T, Houlden H, Cavaleri F, Nagano M, Drummond N, Taanman J-W et al..  2011.  Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus.Nat Commun. 2:440.

Sullivan G, Hay DC, Park I-H, Fletcher J, Hannoun Z, Payne C, Dalgetty D, Black JR, Ross JA, Samuel K et al..  2010.  Generation of functional human hepatic endoderm from human induced pluripotent stem cells.Hepatology. 51(1):329-35.

Sullivan G, Bai Y, Fletcher J, Wilmut I.  2010.  Induced pluripotent stem cells: epigenetic memories and practical implications.Mol Hum Reprod. 16(12):880-5.

Buecker C, Chen H-H, Polo JMaria, Daheron L, Bu L, Barakat TStefan, Okwieka P, Porter A, Gribnau J, Hochedlinger K et al..  2010.  A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.Cell Stem Cell. 6(6):535-46.

Medine C.N, Greenhough S, Hay DC.  2010.  Role of stem-cell-derived hepatic endoderm in human drug discovery.Biochem Soc Trans. 38(4):1033-6.

Navarro P, Chambers I.  2010.  Is the umbilical cord a lifeline for regenerative therapy?Cell Cycle. 9(8):1464.

O'Malley J, Woltjen K, Kaji K.  2009.  New strategies to generate induced pluripotent stem cells.Curr Opin Biotechnol. 20(5):516-21.

Hall J, Guo G, Wray J, Eyres I, Nichols J, Grotewold L, Morfopoulou S, Humphreys P, Mansfield W, Walker R et al..  2009.  Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.Cell Stem Cell. 5(6):597-609.

Vallier L, Touboul T, Brown S, Cho C, Bilican B, Alexander M, Cedervall J, Chandran S, Ahrlund-Richter L, Weber A et al..  2009.  Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells.Stem Cells. 27(11):2655-66.