Leading science, pioneering therapies

CRM Publications

Found 8 results
Filters: Keyword is DNA Restriction Enzymes  [Clear All Filters]
2013
Roberts GA, Chen K, Bower EKM, Madrzak J, Woods A, Barker AM, Cooper LP, White JH, Blakely GW, Manfield I et al..  2013.  Mutations of the domain forming the dimeric interface of the ArdA protein affect dimerization and antimodification activity but not antirestriction activity.FEBS J. 280(19):4903-14.
2012
Roberts GA, Stephanou AS, Kanwar N, Dawson A, Cooper LP, Chen K, Nutley M, Cooper A, Blakely GW, Dryden DTF.  2012.  Exploring the DNA mimicry of the Ocr protein of phage T7.Nucleic Acids Res. 40(16):8129-43.
Roberts GA, Chen K, Cooper LP, White JH, Blakely GW, Dryden DTF.  2012.  Removal of a frameshift between the hsdM and hsdS genes of the EcoKI Type IA DNA restriction and modification system produces a new type of system and links the different families of Type I systems.Nucleic Acids Res. 40(21):10916-24.
Kennaway CK, Taylor JE, Song CFeng, Potrzebowski W, Nicholson W, White JH, Swiderska A, Obarska-Kosinska A, Callow P, Cooper LP et al..  2012.  Structure and operation of the DNA-translocating type I DNA restriction enzymes.Genes Dev. 26(1):92-104.
2011
Roberts GA, Cooper LP, White JH, Su T-J, Zipprich JT, Geary P, Kennedy C, Dryden DTF.  2011.  An investigation of the structural requirements for ATP hydrolysis and DNA cleavage by the EcoKI Type I DNA restriction and modification enzyme.Nucleic Acids Res. 39(17):7667-76.
2010
Serfiotis-Mitsa D, Herbert AP, Roberts GA, Soares DC, White JH, Blakely GW, Uhrín D, Dryden DTF.  2010.  The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro.Nucleic Acids Res. 38(5):1723-37.
2009
Stephanou AS, Roberts GA, Tock MR, Pritchard EH, Turkington R, Nutley M, Cooper A, Dryden DTF.  2009.  A mutational analysis of DNA mimicry by ocr, the gene 0.3 antirestriction protein of bacteriophage T7.Biochem Biophys Res Commun. 378(1):129-32.
1986
Chambers I, Frampton J, Goldfarb P, Affara N, McBain W, Harrison PR.  1986.  The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the 'termination' codon, TGA.EMBO J. 5(6):1221-7.